17alpha)-alph
Yohimbine hydrochloride
CAS: 65-19-0
Molecular Formula: C21H27ClN2O3
17alpha)-alph - Names and Identifiers
| Name | Yohimbine hydrochloride |
| Synonyms | YOHIMBE HCL QUERBRACHINE YOHIMBINE HCL Yohimbine HCL 17alpha)-alph Yohimbine hydrochloride YOHIMBINE HYDROCHLORIDE (16alpha,17alpha)-17-hydroxy-16-(methoxycarbonyl)yohimban-4-ium methyl (17alpha)-17-hydroxyyohimban-16-carboxylate hydrochloride 17-HYDROXYYOHIMBAN-16-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE 17A-HYDROXYYOHIMBAN-16A-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE methyl (3beta,15beta,16beta,17beta,20alpha)-17-hydroxyyohimban-16-carboxylate Yohimban-16-alpha-carboxylic acid, 17-alpha-hydroxy, methyl ester, monohydrochloride |
| CAS | 65-19-0 |
| EINECS | 200-600-4 |
| InChI | InChI=1/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/p+1/t12-,15-,17-,18-,19+/m0/s1 |
| InChIKey | PIPZGJSEDRMUAW-VJDCAHTMSA-N |
17alpha)-alph - Physico-chemical Properties
| Molecular Formula | C21H27ClN2O3 |
| Molar Mass | 390.9 |
| Melting Point | 288-290°C (dec.)(lit.) |
| Boling Point | 542.979°C at 760 mmHg |
| Specific Rotation(α) | 99 º (c=1%, H2O, dry subst) |
| Flash Point | 282.184°C |
| Solubility | Easily soluble in chloroform, soluble in methanol and ethanol, slightly soluble in water. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | White fine powder |
| Color | white to off-white |
| Merck | 14,10102 |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Light Sensitive |
| Refractive Index | 103 ° (C=1, H2O) |
| MDL | MFCD00012674 |
| In vitro study | Yohimbine(Antagonil) is used as a mydriatic and also in the treatment of impotence. It is also considered to be a drug. Yohimbine is a presynaptic Alpha 2 adrenergic blocker. Yohimbine exerts a beneficial effect on erectile function by blocking central α2 Adrenergic receptors, acting on parasympathetic nerves to increase the release of norepinephrine and the rate of excitation of cells in the noradrenergic nuclei of the brain. |
| In vivo study | LD50: Mouse 55 mg/kg (I. p.) |
17alpha)-alph - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R33 - Danger of cumulative effects R23/24 - |
| Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN 1544 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | ZG1015000 |
| TSCA | Yes |
| HS Code | 29339900 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
17alpha)-alph - Reference
| Reference Show more | Effects of dexmedetomidine and yohimbine on depression in chronically stressed mice [J]. Journal of Xuzhou Medical University 2019 039(002):P.115-118. |
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View History
17alpha)-alph
P-chlorophenylhydrazine hcl
Humicacids,sodiumsalt
Acetic acid 3-fluorophenyl ester
钯块
Methyl dodecanoate
P-chlorophenylhydrazine hcl
Humicacids,sodiumsalt
Acetic acid 3-fluorophenyl ester
钯块
Methyl dodecanoate