179246-45-8
Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-
CAS: 179246-45-8
Molecular Formula: C13H11ClFNO
179246-45-8 - Names and Identifiers
| Name | Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]- |
| Synonyms | Lapatinib impurity E 4-(2-fluorobenzyloxy)-3-chlorobenzenaMine 4-(2-fluorobenzyloxy)-3-chlorobenzenamine Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]- |
| CAS | 179246-45-8 |
| InChI | InChI=1S/C13H11ClFNO/c14-11-7-10(16)5-6-13(11)17-8-9-3-1-2-4-12(9)15/h1-7H,8,16H2 |
179246-45-8 - Physico-chemical Properties
| Molecular Formula | C13H11ClFNO |
| Molar Mass | 251.68 |
| Density | 1.306±0.06 g/cm3(Predicted) |
| Boling Point | 390.5±32.0 °C(Predicted) |
| pKa | 3.95±0.10(Predicted) |
179246-45-8 - Introduction
Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is an organic compound with the chemical formula C13H11ClFNO. The following is an introduction to its nature, use, preparation and safety information:
Nature:
1. Appearance: Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is colorless or light yellow crystal.
2. Melting Point: its melting point range is 90-92 ° C.
3. Solubility: It is soluble in organic solvents such as acetone, chloroform and dimethylformamide at room temperature.
Use:
The main use of Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is as an intermediate in organic synthesis. It can be used in the synthesis of fluorescent dyes, pharmaceutical preparations and pesticides and other compounds.
Method:
A commonly used preparation method is to obtain Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-through the substitution reaction of p-chloroaniline-. The specific steps are first reacting chloroaniline with 2-fluorobenzyl alcohol, and adding a cuprous chloride catalyst. After completion of the reaction, the product was purified by the steps of crystallization, filtration, and washing.
Safety Information:
1. Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-General laboratory safety procedures should be followed during handling and storage, including wearing protective glasses and gloves.
2. It is a toxic compound, avoid contact with the skin and inhalation of its vapors. Adequate ventilation shall be provided during handling.
3. If taken by mistake or inhaled, consult a doctor immediately and provide details of the compound.
Nature:
1. Appearance: Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is colorless or light yellow crystal.
2. Melting Point: its melting point range is 90-92 ° C.
3. Solubility: It is soluble in organic solvents such as acetone, chloroform and dimethylformamide at room temperature.
Use:
The main use of Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-is as an intermediate in organic synthesis. It can be used in the synthesis of fluorescent dyes, pharmaceutical preparations and pesticides and other compounds.
Method:
A commonly used preparation method is to obtain Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-through the substitution reaction of p-chloroaniline-. The specific steps are first reacting chloroaniline with 2-fluorobenzyl alcohol, and adding a cuprous chloride catalyst. After completion of the reaction, the product was purified by the steps of crystallization, filtration, and washing.
Safety Information:
1. Benzenamine, 3-chloro-4-[(2-fluorophenyl)methoxy]-General laboratory safety procedures should be followed during handling and storage, including wearing protective glasses and gloves.
2. It is a toxic compound, avoid contact with the skin and inhalation of its vapors. Adequate ventilation shall be provided during handling.
3. If taken by mistake or inhaled, consult a doctor immediately and provide details of the compound.
Last Update：2024-04-09 02:00:43
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Product Name: 4-(2-fluorobenzyloxy)-3-chlorobenzenaMine Request for quotationCAS: 179246-45-8
Tel: 0712-8899838
Email: jy6101@rmastandards.com
Mobile: 86-15787876101
QQ: 2518299249
Wechat: 15787876101
Spot supply
Product Name: 4-(2-fluorobenzyloxy)-3-chlorobenzenamine Visit Supplier Webpage Request for quotationCAS: 179246-45-8
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
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View History
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tert-Butylthiourea
氧氯化锆 溶液
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氟啶虫胺腈
147969-86-6
八水合硫酸镉
SODIUM 2-KETOBUTYRATE
24134-09-6