17918-14-8

17918-14-8 - Names and Identifiers

Name	2,5-dimethoxybenzoyl chloride
Synonyms	2,5-Dimethoxybenzoyl chloride 2,5-DIMETHOXYBENZOYL CHLORIDE 2,5-dimethoxybenzoyl chloride Benzoyl chloride, 2,5-dimethoxy- 2,5-Dimethoxybenzoic acid chloride 2,5-DIMETHOXYBENZENE-1-CARBONYL CHLORIDE carbamic acid [5-[(3-nitrophenyl)thio]-4-propan-2-yl-1-prop-2-enyl-2-imidazolyl]methyl ester
CAS	17918-14-8
EINECS	241-863-5
InChI	InChI=1/C9H9ClO3/c1-12-6-3-4-8(13-2)7(5-6)9(10)11/h3-5H,1-2H3

17918-14-8 - Physico-chemical Properties

Molecular Formula	C9H9ClO3
Molar Mass	200.62
Density	1.224g/cm³
Boling Point	179°C/10mm
Flash Point	134.1°C
Vapor Presure	0.000757mmHg at 25°C
Refractive Index	1.52

17918-14-8 - Introduction

Nature:
2,5-dimethoxybenzoyl chloride is a colorless to pale yellow liquid with a spicy smell. It can decompose at room temperature, so you need to be careful when handling it. The compound is hardly soluble in water, but soluble in organic solvents such as ether and chloroform.

Use:
2,5-dimethoxybenzoyl chloride is commonly used as a reagent in organic synthesis. It can be used as a synthetic intermediate of benzimide, and is often used to introduce methoxy groups in organic synthesis.

Method:
A commonly used method for preparing 2,5-dimethoxybenzoyl chloride is to react 2,5-dimethoxybenzoic acid with a certain proportion of thionyl chloride in the presence of sulfuric acid. After the reaction, the excess bisulfite produced is neutralized by adding water and sodium carbonate solution, and then the product is extracted with ether to obtain 2,5-dimethoxybenzoyl chloride.

Safety Information:
2,5-dimethoxybenzoyl chloride is an organic halogenated acid compound, which has certain danger. Protective glasses and gloves must be worn during operation to avoid contact with skin and eyes. It should be stored in a sealed container, avoid contact with oxygen, moisture and strong oxidants. In addition, the relevant safe handling regulations for chemicals must be observed during their preparation and use.

Last Update：2024-04-09 20:52:54