1722-62-9
mepivacaine hydrochloride
CAS: 1722-62-9
Molecular Formula: C15H22N2O.ClH
1722-62-9 - Names and Identifiers
1722-62-9 - Physico-chemical Properties
| Molecular Formula | C15H22N2O.ClH |
| Molar Mass | 282.81 |
| Melting Point | 255-257°C (dec.) |
| Boling Point | 383.1°C at 760 mmHg |
| Flash Point | 185.5°C |
| Solubility | H2O: soluble20mg/mL, clear |
| Vapor Presure | 4.52E-06mmHg at 25°C |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | 2-8°C |
| In vitro study | Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action. Mepivacaine hydrochloride has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine). Mepivacaine hydrochloride displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels. |
| In vivo study | Tests on horses have shown that mepivacaine has a greater spread between adjacent joint structures than postulated after latex injection based on previous dissections, in contrast to arthrographic studies. In patients undergoing knee arthroscopy, sonication reduced the minimum effective anesthetic volume (MEAV50) required for 1.5 mepivacaine blockade of the sciatic nerve by 37% compared to nerve stimulation. In canines and premolars, the use of lidocaine preparation 3% mepivacaine resulted in shorter intervals of anesthesia compared with epinephrine. |
1722-62-9 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| UN IDs | UN 2811 6.1 / PGIII |
| RTECS | TK6475000 |
| HS Code | 29333990 |
| Toxicity | LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg) |
Supplier List
Multiple SpecificationsSpot supply
Product Name: Mepivacaine Hydrochloride Request for quotationCAS: 1722-62-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Mepivacaine hydrochloride Visit Supplier Webpage Request for quotationCAS: 1722-62-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Mepivacaine Visit Supplier Webpage Request for quotationCAS: 1722-62-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: mepivacaine hydrochloride Visit Supplier Webpage Request for quotationCAS: 1722-62-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Multiple SpecificationsSpot supply
Product Name: Mepivacaine Hydrochloride Request for quotationCAS: 1722-62-9
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Mepivacaine hydrochloride Visit Supplier Webpage Request for quotationCAS: 1722-62-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Multiple SpecificationsSpot supply
Product Name: Mepivacaine Visit Supplier Webpage Request for quotationCAS: 1722-62-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: mepivacaine hydrochloride Visit Supplier Webpage Request for quotationCAS: 1722-62-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
View History