1638-75-1
CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE
CAS: 1638-75-1
Molecular Formula: C3H8ClOP
1638-75-1 - Names and Identifiers
1638-75-1 - Physico-chemical Properties
| Molecular Formula | C3H8ClOP |
| Molar Mass | 126.52 |
| Density | 1.113±0.06 g/cm3(Predicted) |
| Melting Point | 70.5-71 °C |
| Boling Point | 80-83 °C(Press: 1 Torr) |
1638-75-1 - Introduction
CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is an organophosphorus compound with the chemical formula (CH3)2 POCH2Cl. The following is an introduction to the nature, use, formulation and safety information of CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE:
Nature:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is a colorless or pale yellow liquid with a pungent odor.
-It is soluble in organic solvents such as ethanol, ethers and chlorinated hydrocarbons, but insoluble in water.
-It is an organic electrophilic reagent with strong electrophilicity and is easy to react with nucleophiles.
Use:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE can be used for oxidation and phosphating reactions in organic synthesis.
-It is commonly used as a reagent for the establishment of phosphorus heterocycles, nucleophilic substitution reactions of alcohol ethers, and phosphine oxide propanol rearrangement reactions of esters.
Preparation Method:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE can be prepared by the reaction of methyl chloromethyl phosphine chloride and trimethylamine.
Safety Information:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is irritating and corrosive, be careful to wear personal protective equipment such as gloves, goggles and lab coats when handling.
-Flammability, avoid contact with open flame and oxygen.
-Storage should avoid high temperature and direct sunlight. It is recommended to store in a cool and ventilated place, and avoid mixing with other organic substances and oxidants.
-in the use and disposal process should be strictly in accordance with the relevant safety operation specifications for operation, to prevent harm to the human body and the environment.
Nature:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is a colorless or pale yellow liquid with a pungent odor.
-It is soluble in organic solvents such as ethanol, ethers and chlorinated hydrocarbons, but insoluble in water.
-It is an organic electrophilic reagent with strong electrophilicity and is easy to react with nucleophiles.
Use:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE can be used for oxidation and phosphating reactions in organic synthesis.
-It is commonly used as a reagent for the establishment of phosphorus heterocycles, nucleophilic substitution reactions of alcohol ethers, and phosphine oxide propanol rearrangement reactions of esters.
Preparation Method:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE can be prepared by the reaction of methyl chloromethyl phosphine chloride and trimethylamine.
Safety Information:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is irritating and corrosive, be careful to wear personal protective equipment such as gloves, goggles and lab coats when handling.
-Flammability, avoid contact with open flame and oxygen.
-Storage should avoid high temperature and direct sunlight. It is recommended to store in a cool and ventilated place, and avoid mixing with other organic substances and oxidants.
-in the use and disposal process should be strictly in accordance with the relevant safety operation specifications for operation, to prevent harm to the human body and the environment.
Last Update：2024-04-10 22:29:15
