163733-99-1
4-AMINO-2,3-DIFLUORO-PHENOL
CAS: 163733-99-1
Molecular Formula: C6H5F2NO
163733-99-1 - Names and Identifiers
| Name | 4-AMINO-2,3-DIFLUORO-PHENOL |
| Synonyms | 4-AMINO-2,3-DIFLUORO-PHENOL 4-cyano-2-fluorobenzoic acid 2,3-DIFLUORO-4-HYDROXYANILINE Phenol, 4-amino-2,3-difluoro- Phenol, 4-amino-2,3-difluoro- (9CI) |
| CAS | 163733-99-1 |
| InChI | InChI=1/C6H5F2NO/c7-5-3(9)1-2-4(10)6(5)8/h1-2,10H,9H2 |
163733-99-1 - Physico-chemical Properties
| Molecular Formula | C6H5F2NO |
| Molar Mass | 145.11 |
| Density | 1.472±0.06 g/cm3(Predicted) |
| Melting Point | ca 153℃ |
| Boling Point | 255.5±40.0 °C(Predicted) |
| Flash Point | 108.3°C |
| Vapor Presure | 0.0101mmHg at 25°C |
| pKa | 7.99±0.23(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Refractive Index | 1.57 |
163733-99-1 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Note | Irritant |
163733-99-1 - Introduction
4-AMINO-2, 3-difluoro-phenol is an organic compound with the chemical formula C6H5F2NO. The following is a description of its nature, use, preparation and safety information:
Nature:
4-AMINO-2, 3-difluoro-phenol is a solid, colorless crystal at room temperature. It is less soluble in water, but can be dissolved in organic solvents. It is a weak acid that can react with hydrogen ions in bases through protonation reactions.
Use:
4-AMINO-2, 3-difluoro-phenol is commonly used as a catalyst and intermediate in organic synthesis. It can be used as a raw material for the synthesis of drugs, such as the synthesis of certain non-steroidal anti-inflammatory drugs. In addition, it can also be used as a synthetic intermediate for organic dyes and pigments.
Method:
The preparation of 4-AMINO-2, 3-difluoro-phenol can be carried out by various methods. One of the common methods is the reaction of 2,3-difluorophenol with ammonia, usually under alkaline conditions. The reaction process generally requires higher temperatures and longer times.
Safety Information:
Due to the particularity of the nature and use of chemicals, the following safety precautions should be paid attention to when using and handling:
1. Must ensure that the operating environment is well ventilated, avoid inhalation of gas, steam, mist or dust.
2. Wear appropriate personal protective equipment, such as gloves, protective glasses, protective masks and protective clothing.
3. Avoid contact with skin and eyes, such as accidental contact, please rinse immediately with plenty of water.
4. Avoid swallowing or ingesting the compound. If eaten by mistake, seek medical help.
5. When storing, it should be stored in a cool, dry and sealed container, away from fire and oxidizing agents.
Please note that the above content is only a general description of 4-AMINO-2, 3-difluoro-phenol. The specific use should be handled and operated according to actual needs and conditions.
Nature:
4-AMINO-2, 3-difluoro-phenol is a solid, colorless crystal at room temperature. It is less soluble in water, but can be dissolved in organic solvents. It is a weak acid that can react with hydrogen ions in bases through protonation reactions.
Use:
4-AMINO-2, 3-difluoro-phenol is commonly used as a catalyst and intermediate in organic synthesis. It can be used as a raw material for the synthesis of drugs, such as the synthesis of certain non-steroidal anti-inflammatory drugs. In addition, it can also be used as a synthetic intermediate for organic dyes and pigments.
Method:
The preparation of 4-AMINO-2, 3-difluoro-phenol can be carried out by various methods. One of the common methods is the reaction of 2,3-difluorophenol with ammonia, usually under alkaline conditions. The reaction process generally requires higher temperatures and longer times.
Safety Information:
Due to the particularity of the nature and use of chemicals, the following safety precautions should be paid attention to when using and handling:
1. Must ensure that the operating environment is well ventilated, avoid inhalation of gas, steam, mist or dust.
2. Wear appropriate personal protective equipment, such as gloves, protective glasses, protective masks and protective clothing.
3. Avoid contact with skin and eyes, such as accidental contact, please rinse immediately with plenty of water.
4. Avoid swallowing or ingesting the compound. If eaten by mistake, seek medical help.
5. When storing, it should be stored in a cool, dry and sealed container, away from fire and oxidizing agents.
Please note that the above content is only a general description of 4-AMINO-2, 3-difluoro-phenol. The specific use should be handled and operated according to actual needs and conditions.
Last Update：2024-04-09 20:52:54
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