159634-80-7

159634-80-7 - Names and Identifiers

Name	tert-butyl spiro[2,3-dihydro-1H-isoquinoline-4,4'-piperidine]-1'-carboxylate
Synonyms	LogP TERT-BUTYL 2,3-DIHYDRO-1H-SPIRO[ISOQUINOLINE-4,4'-PIPERIDINE]-1'-CARBOXYLATE tert-butyl spiro[2,3-dihydro-1H-isoquinoline-4,4'-piperidine]-1'-carboxylate 2,3-Dihydro-spiro[isoquinolin-4(1H),4'-piperidine]-1'-carboxylic acid tert-butyl ester 2,3-dihydro-Spiro[isoquinoline-4(1H),4'-piperidine]-1'-carboxylic acid 1,1-dimethylethyl ester 1,2,3,4-tetrahydrospiro[isoquinolin-4,4'-piperidine]-1'-carboxylic acid, 1,1-diMethylethyl ester Spiro[isoquinoline-4(1H),4'-piperidine]-1'-carboxylic acid, 2,3-dihydro-, 1,1-diMethylethyl ester
CAS	159634-80-7
InChI	InChI=1/C18H26N2O2/c1-17(2,3)22-16(21)20-10-8-18(9-11-20)13-19-12-14-6-4-5-7-15(14)18/h4-7,19H,8-13H2,1-3H3

159634-80-7 - Physico-chemical Properties

Molecular Formula	C18H26N2O2
Molar Mass	302.41
Density	1.13±0.1 g/cm3(Predicted)
Boling Point	428.5±45.0 °C(Predicted)
Flash Point	212.949°C
Vapor Presure	0mmHg at 25°C
pKa	9.44±0.20(Predicted)
Storage Condition	2-8℃
Refractive Index	1.571

159634-80-7 - Introduction

spiro[2, tert-butyl, 4 '-piperidine]-1'-carboxylate is an organic compound with the chemical formula C18H22N2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: tert-butyl spiro[2, 4 '-piperidine]-1'-carboxylate is a white crystalline solid.
-Density: Its density is 1.17g/cm³.
-Melting point: Its melting point is 79-83°C.
-Solubility: Soluble in organic solvents such as ether, dimethylformamide and chloroform.

Use:
- tert-butyl spiro[2, 4 '-piperidine]-1'-carbonate is a widely used chemical reagent commonly used in organic synthesis reactions.
-It plays an important role in the preparation of drugs in the field of medicine, such as the synthesis of potassium oxalate channel openers (such as Ro 31-6930).

Method:
- tert-butyl spiro[2, 4 '-piperidine]-1'-carboxylate is usually prepared by organic synthesis methods.
-specific synthesis process can refer to the relevant organic chemical synthesis literature or patent.

Safety Information:
- tert-butyl spiro[2, 4 '-piperidine]-1'-carboxylate is a chemical, attention should be paid to protective measures, such as wearing appropriate protective glasses, gloves and laboratory coats, pay attention to ventilation during operation.
-During operation, avoid contact with skin or inhalation of dust or gas.
-In case of contact, rinse contaminated skin immediately with plenty of water and seek medical attention immediately.
-Waste should be disposed of in accordance with local regulations and safety regulations.

The above is a brief introduction to the nature, use, preparation and safety information of tert-butyl spiro[2, 4 '-piperidine]-1'-carboxylate. When using and handling the compound, Please strictly follow the relevant safety procedures to ensure the safety of personnel and the environment.

Last Update：2024-04-09 19:05:47