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159414-99-0

N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

CAS: 159414-99-0

Molecular Formula: C41H49FN5O8P

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159414-99-0 - Names and Identifiers

Name N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
Synonyms Ac-2'-F-dC Phosphoramidite
2'-F-Ac-dC Phosphoramidite
2'-F-Ac-dC Phosphoramidite
2'-F-rC(N-Ac) Phosphoramidite
5'-O-DMT-2'-F-dC(N-Ac)-3'-CEDPA
N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite
N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
CAS 159414-99-0
EINECS 2017-001-1

159414-99-0 - Physico-chemical Properties

Molecular FormulaC41H49FN5O8P
Molar Mass789.83
Appearancepowder
Colorwhite to off-white
pKa10.11±0.20(Predicted)
Storage ConditionSealed in dry,Store in freezer, under -20°C

159414-99-0 - Risk and Safety

WGK Germany3

159414-99-0 - Introduction

N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is an organic compound with the following properties:

1. Appearance: generally solid, common for white crystal or powder.
2. Molecular formula: C36H38FN4O9P
3. Molecular weight: 730.68g/mol
4. Solubility: N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is soluble in DMSO (dimethyl sulfoxide), ethanol and methanol.

N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is mainly used as a biologically active compound, it is often used as an intermediate in drug research and development. The compound plays an important role in the research of antiviral drugs.

When preparing N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite, different synthesis strategies are often used. A common approach is to use multi-step reactions in the synthesis process, including substitution and esterification reactions, to produce the desired product. Specific synthesis details refer to the relevant literature or patent.

For safety information, N-Acetyl-5 '-O-(4,4-dimethoxytrityl)-2'-deoxy-2 '-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl) the toxicity and safety of phosphoramidite require further study and evaluation. Since it is a newly synthesized compound, its toxicity and danger have not been determined. During operation and use, follow appropriate laboratory safety practices, including wearing appropriate protective equipment, following correct operating methods, and proper handling and disposal of waste. At the same time, it is recommended to use the compound under the guidance of professionals and follow relevant regulations and regulations.
Last Update:2024-04-09 21:04:16
159414-99-0
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