153034-80-1
2-FLUORO-4-IODO-3-PICOLINE
CAS: 153034-80-1
Molecular Formula: C6H5FIN
153034-80-1 - Names and Identifiers
| Name | 2-FLUORO-4-IODO-3-PICOLINE |
| Synonyms | 2-FLUORO-4-IODO-3-PICOLINE 2-Fluoro-4-iodo-3-methylpyridine Pyridine, 2-fluoro-4-iodo-3-methyl- |
| CAS | 153034-80-1 |
| InChI | InChI=1/C6H5FIN/c1-4-5(8)2-3-9-6(4)7/h2-3H,1H3 |
153034-80-1 - Physico-chemical Properties
| Molecular Formula | C6H5FIN |
| Molar Mass | 237.01 |
| Density | 1.892 |
| Boling Point | 244℃ |
| Flash Point | 101℃ |
| Vapor Presure | 0.05mmHg at 25°C |
| pKa | -1.53±0.18(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.587 |
153034-80-1 - Introduction
2-FLUORO-4-IODO-3-PICOLINE is an organic compound with the chemical formula C6H5FIN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-FLUORO-4-IODO-3-PICOLINE in the form of white crystals or powder.
-Melting point: About 75-77 ° C.
-Boiling point: About 228-230 ° C.
-Solubility: It dissolves in ethanol, chloroform and dichloromethane, but has low solubility in water.
Use:
- 2-FLUORO-4-IODO-3-PICOLINE is an organic synthesis intermediate, commonly used in the synthesis of other organic compounds.
-It can also be used as a raw material in the pharmaceutical field for the synthesis of drugs or pharmaceutical intermediates.
Method:
The preparation of-2-FLUORO-4-IODO-3-PICOLINE can be achieved by iodination reaction and fluorination reaction.
-A commonly used preparation method is to react 2-amino-3-methyl-4-iodopyridine with hydrogen fluoride to produce 2-fluororo-4-iodo-3-picoline.
Safety Information:
- 2-FLUORO-4-IODO-3-PICOLINE is relatively stable at room temperature, but it may decompose under the action of high temperature and fire source, producing toxic gas.
-During use, avoid inhaling the dust or vapor of the substance, and avoid contact with skin and eyes.
-When handling or storing 2-FLUORO-4-IODO-3-PICOLINE, take appropriate safety measures, such as wearing protective gloves, masks and glasses, and ensure good ventilation.
Nature:
-Appearance: 2-FLUORO-4-IODO-3-PICOLINE in the form of white crystals or powder.
-Melting point: About 75-77 ° C.
-Boiling point: About 228-230 ° C.
-Solubility: It dissolves in ethanol, chloroform and dichloromethane, but has low solubility in water.
Use:
- 2-FLUORO-4-IODO-3-PICOLINE is an organic synthesis intermediate, commonly used in the synthesis of other organic compounds.
-It can also be used as a raw material in the pharmaceutical field for the synthesis of drugs or pharmaceutical intermediates.
Method:
The preparation of-2-FLUORO-4-IODO-3-PICOLINE can be achieved by iodination reaction and fluorination reaction.
-A commonly used preparation method is to react 2-amino-3-methyl-4-iodopyridine with hydrogen fluoride to produce 2-fluororo-4-iodo-3-picoline.
Safety Information:
- 2-FLUORO-4-IODO-3-PICOLINE is relatively stable at room temperature, but it may decompose under the action of high temperature and fire source, producing toxic gas.
-During use, avoid inhaling the dust or vapor of the substance, and avoid contact with skin and eyes.
-When handling or storing 2-FLUORO-4-IODO-3-PICOLINE, take appropriate safety measures, such as wearing protective gloves, masks and glasses, and ensure good ventilation.
Last Update：2024-04-09 02:00:42
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