1511861-89-4
2-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid, Mixture of diastereomers
CAS: 1511861-89-4
Molecular Formula: C11H10ClFO2
1511861-89-4 - Names and Identifiers
1511861-89-4 - Physico-chemical Properties
| Molecular Formula | C11H10ClFO2 |
| Molar Mass | 228.65 |
1511861-89-4 - Introduction
2-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid, Mixture of diastereomers is a compound with the formula C13H11ClF2O2. It is a mixture of two enantiomers. The following is a detailed description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: White solid
-Melting point: about 135-140 ° C
-Solubility: Slightly soluble in water, soluble in organic solvents such as chloroform, ethanol and dimethyl sulfoxide (DMSO)
Use:
2-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid, Mixture of diasteromers has certain application value in drug synthesis. It can be used as a drug intermediate for the synthesis of some drugs, such as anti-cancer drugs, antiviral drugs and so on. In addition, it can also be used as a research compound for the study of specific chemical reactions and their applications.
Method:
The specific synthesis method can be adjusted according to different literature and research. A common preparation method is to obtain 1-(4-chloro-2-fluorophenyl) cyclobutan-1-ol by the reaction of ethyl borofluoride and 4-chloro-2-fluorophenylcarbaldehyde, then 1-(4-chloro-2-fluorophenyl) cyclobutane -1-ether was obtained by acid-catalyzed dehydration reaction, and finally the target product was obtained by reduction and acid hydrolysis.
Safety Information:
When using 2-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid, mix of diastereomers, pay attention to safety operation. It may cause irritation to the eyes, skin and respiratory system, so appropriate personal protective equipment such as lab gloves, glasses and masks are required. In addition, avoid inhaling or coming into contact with its dust, fumes or gases. In storage and handling, standard operating procedures for chemicals should be followed and placed in sealed containers, away from ignition and oxidizing agents. In any case, if necessary, please carefully read and follow the Chemical Safety Data Sheet (MSDS) or relevant safety operation guidelines.
Nature:
-Appearance: White solid
-Melting point: about 135-140 ° C
-Solubility: Slightly soluble in water, soluble in organic solvents such as chloroform, ethanol and dimethyl sulfoxide (DMSO)
Use:
2-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid, Mixture of diasteromers has certain application value in drug synthesis. It can be used as a drug intermediate for the synthesis of some drugs, such as anti-cancer drugs, antiviral drugs and so on. In addition, it can also be used as a research compound for the study of specific chemical reactions and their applications.
Method:
The specific synthesis method can be adjusted according to different literature and research. A common preparation method is to obtain 1-(4-chloro-2-fluorophenyl) cyclobutan-1-ol by the reaction of ethyl borofluoride and 4-chloro-2-fluorophenylcarbaldehyde, then 1-(4-chloro-2-fluorophenyl) cyclobutane -1-ether was obtained by acid-catalyzed dehydration reaction, and finally the target product was obtained by reduction and acid hydrolysis.
Safety Information:
When using 2-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid, mix of diastereomers, pay attention to safety operation. It may cause irritation to the eyes, skin and respiratory system, so appropriate personal protective equipment such as lab gloves, glasses and masks are required. In addition, avoid inhaling or coming into contact with its dust, fumes or gases. In storage and handling, standard operating procedures for chemicals should be followed and placed in sealed containers, away from ignition and oxidizing agents. In any case, if necessary, please carefully read and follow the Chemical Safety Data Sheet (MSDS) or relevant safety operation guidelines.
Last Update：2024-04-09 20:52:54
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Spot supply
Product Name: 1-(4-chloro-2-fluorophenyl)cyclobutane-1-carboxylic acid Visit Supplier Webpage Request for quotationCAS: 1511861-89-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
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