147969-86-6

147969-86-6 - Names and Identifiers

Name	1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-(1,1-dimethylethyl) ester
Synonyms	1-Boc-4-(4-carboxy-benzyl)-piperidine 4-[(1-BOC-4-PIPERIDINYL)METHYL]BENZOIC ACID [4-(N-BOC-PIPERIDINYL)METHYL]-4-BENZOIC ACID 4-((1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)METHYL)BENZOIC ACID 1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-... 1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-(1,1-dimethylethyl) ester 1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-, 1-(1,1-dimethylethyl) ester
CAS	147969-86-6

147969-86-6 - Physico-chemical Properties

Molecular Formula	C18H25NO4
Molar Mass	319.4
Storage Condition	Room Temprature

147969-86-6 - Introduction

1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-(1,1-dimenthylethyl) ester is an organic compound, the structure contains a 4-piperidinylmethyl group and a benzoic acid group, and the compound is modified by a protected carboxymethyl group (with a Boc protecting group).

Regarding its properties, 1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-(1,1-dimethylethyl) ester is solid, soluble in some organic solvents and in solution under acidic conditions. It is stable at room temperature, but sensitive to light and oxygen.

One of its main uses is as an intermediate in organic synthesis. It can be used in the preparation of drugs, dyes and the introduction of specific functional groups and other reactions. In addition, it can also be used as a raw material for photoresist and the synthesis of surfactants.

Preparation of 1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-(1,1-dimethylethyl) the method of ester is generally by reacting 4-aminobenzoic acid with 1-boc-4-piperidinemethanol to form the compound. Specifically, 4-aminobenzoic acid can be first reacted with an appropriate amount of concentrated hydrochloric acid or sulfuric acid solution, then an appropriate amount of relatively dry n-Butanol is added, and then the reaction mixture is cooled to a low temperature, finally, 1-boc-4-piperidinemethanol was slowly added and reacted for several hours. The product obtained can be obtained by crystallization, filtration and drying.

Regarding safety information, 1-Piperidinecarboxylic acid, 4-[(4-carboxyphenyl)methyl]-,1-(1,1-dimethylethyl) ester is dangerous. It may cause irritation to the eyes, skin, respiratory tract and digestive system. It must be used under well-ventilated conditions and avoid inhalation, contact with skin and eyes. Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing during use. Appropriate safety procedures should be followed during storage and handling, and it should be kept in a dry, cool place. In case of inhalation or contact, seek medical attention immediately.

Last Update：2024-04-09 21:54:55