146548-59-6 - Names and Identifiers
| Name | 2,4,6-trimethoxybenzylamine hydrochloride
|
| Synonyms | TIMTEC-BB SBB003257 2,4,6-Trimethoxybenz 2,4,6-TrimethoxybenzylamineHCl (2S)-2-amino-3-methylbutan-1-ol 1-(2,4,6-trimethoxyphenyl)methanamine 2,4,6-Trimethoxybenzylamine hydrochloride 2,4,6-trimethoxybenzylamine hydrochloride 2,4,6-TRIMETHOXYBENZYLAMINE HYDROCHLORIDE (2,4,6-triMethoxyphenyl)MethanaMine hydrochloride
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| CAS | 146548-59-6
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| InChI | InChI=1/C10H15NO3/c1-12-7-4-9(13-2)8(6-11)10(5-7)14-3/h4-5H,6,11H2,1-3H3 |
146548-59-6 - Physico-chemical Properties
| Molecular Formula | C10H16ClNO3
|
| Molar Mass | 233.69 |
| Density | 1.087g/cm3 |
| Melting Point | 204-207°C(lit.) |
| Boling Point | 312°C at 760 mmHg |
| Flash Point | 151.1°C |
| Vapor Presure | 0.000544mmHg at 25°C |
| Appearance | Powder |
| Color | White to off-white |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.515 |
146548-59-6 - Risk and Safety
| Hazard Symbols | Xi - Irritant

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| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
| WGK Germany | 3 |
146548-59-6 - Introduction
2,4,6-trimethoxybenzylamine hydrochloride is an organic compound with the chemical formula C10H15NO3 · HCl. The following is a description of some properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: Colorless crystal or white crystalline powder.
-Solubility: Soluble in water, ethanol, chloroform and other organic solvents.
-Melting point: about 160-165°C.
-Density: about 1.18g/cm³.
- pKa: about 9.05 (in 10% aqueous solution).
Use:
- 2,4,6-trimethoxybenzylamine hydrochloride is mainly used as an intermediate and raw material in the field of medicine.
-It can be used to synthesize some drugs, such as antihypertensive drugs, stimulants and some anti-cancer drugs.
-It can also be used as a synthetic intermediate for biguanide drugs.
Method:
2,4,6-trimethoxybenzylamine hydrochloride can be prepared as follows:
-First, benzylamine is reacted with methanol in the presence of a base to obtain 2,4, 6-trimethoxybenzaldehyde.
-Then, 2,4, 6-trimethoxybenzaldehyde is reacted with hydrochloric acid to generate 2,4,6-trimethoxybenzylamine hydrochloride.
Safety Information:
- 2,4,6-trimethoxybenzylamine hydrochloride is a non-lethal chemical, but it is still necessary to pay attention to safe operation.
-Wear suitable personal protective equipment such as gloves, goggles and protective clothing during operation.
-Avoid inhaling its dust and avoid contact with skin and eyes.
-During use and storage, Please strictly abide by the relevant regulations on chemicals and store them in a dry and well-ventilated place.
Last Update:2024-04-09 21:01:54