14527-44-7
Methyl 5-thiazolecarboxylate
CAS: 14527-44-7
Molecular Formula: C5H5NO2S
14527-44-7 - Names and Identifiers
14527-44-7 - Physico-chemical Properties
| Molecular Formula | C5H5NO2S |
| Molar Mass | 143.16 |
| Density | 1.45 |
| Melting Point | 68-69°C |
| Boling Point | 87-90°C (10 mmHg) |
| Flash Point | 86.8°C |
| Vapor Presure | 0.117mmHg at 25°C |
| pKa | 0.80±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.539 |
| MDL | MFCD03788563 |
14527-44-7 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Harmful |
14527-44-7 - Introduction
Methyl 5-thiazolecarboxylate is an organic compound with the chemical formula C6H5NO2S. The following is an introduction to the nature, use, formulation and safety information of Methyl 5-thiazolecarboxylate:
Nature:
Methyl 5-thiazolecarboxylate is a colorless or light yellow liquid with a special sulfide odor. It can be dissolved in organic solvents such as ethanol and dimethylformamide, and is insoluble in water.
Use:
Methyl 5-thiazolecarboxylate has a wide range of applications in drug synthesis. It is an important intermediate for the synthesis of some anticancer drugs and other physiologically active compounds. In addition, it can also be used as a catalyst or solvent in organic synthesis.
Method:
The preparation of Methyl 5-thiazolecarboxylate can be obtained by reacting Methyl acetate and sodium thiosulfate. A specific method is to dissolve sodium thiosulfate and methyl ethyl ester in an organic solvent, and then add sodium carbonate or potassium carbonate. After the reaction is carried out, the product is obtained by crystallization or distillation.
Safety Information:
Methyl 5-thiazolecarboxylate is less harmful to the human body under normal conditions. However, it is a flammable liquid, and care should be taken to avoid exposure to open flames and high temperatures. During operation, attention should be paid to protective measures, such as wearing protective gloves and goggles. At the same time, it should be stored in a sealed container, away from fire and oxidizing agents.
Please note that when using and handling Methyl 5-thiazolecarboxylate, you should follow the correct laboratory safety operating guidelines and consult relevant professionals.
Nature:
Methyl 5-thiazolecarboxylate is a colorless or light yellow liquid with a special sulfide odor. It can be dissolved in organic solvents such as ethanol and dimethylformamide, and is insoluble in water.
Use:
Methyl 5-thiazolecarboxylate has a wide range of applications in drug synthesis. It is an important intermediate for the synthesis of some anticancer drugs and other physiologically active compounds. In addition, it can also be used as a catalyst or solvent in organic synthesis.
Method:
The preparation of Methyl 5-thiazolecarboxylate can be obtained by reacting Methyl acetate and sodium thiosulfate. A specific method is to dissolve sodium thiosulfate and methyl ethyl ester in an organic solvent, and then add sodium carbonate or potassium carbonate. After the reaction is carried out, the product is obtained by crystallization or distillation.
Safety Information:
Methyl 5-thiazolecarboxylate is less harmful to the human body under normal conditions. However, it is a flammable liquid, and care should be taken to avoid exposure to open flames and high temperatures. During operation, attention should be paid to protective measures, such as wearing protective gloves and goggles. At the same time, it should be stored in a sealed container, away from fire and oxidizing agents.
Please note that when using and handling Methyl 5-thiazolecarboxylate, you should follow the correct laboratory safety operating guidelines and consult relevant professionals.
Last Update：2024-04-09 21:11:58
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View History
14527-44-7
一辛基锡
51990-12-6
Sporothriolide
二甲硅油
885269-36-3
288617-76-5
162102-81-0
didecyldimethylammoniumchloride
一辛基锡
51990-12-6
Sporothriolide
二甲硅油
885269-36-3
288617-76-5
162102-81-0
didecyldimethylammoniumchloride