1445993-87-2

1445993-87-2 - Names and Identifiers

Name	4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
Synonyms	4-Bromo-6-methyl-1-tosyl-6-azaindole-7(6H)-one 4-bromo-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 4-bromo-6-methyl-1-tosyl-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one 4-bromo-6-methyl-1-(4-methylbenzenesulfonyl)-1H,6H,7H-pyrrolo[2,3-c]pyridin-7-one 4-bromo-6-methyl-1-[(4-methylphenyl)sulfonyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one 7H-Pyrrolo[2,3-c]pyridin-7-one, 4-bromo-1,6-dihydro-6-methyl-1-[(4-methylphenyl)sulfonyl]-
CAS	1445993-87-2

1445993-87-2 - Physico-chemical Properties

Molecular Formula	C15H13BrN2O3S
Molar Mass	381.24
Density	1.59±0.1 g/cm3(Predicted)
Boling Point	564.2±60.0 °C(Predicted)
pKa	-4.40±0.40(Predicted)
Storage Condition	-20℃

1445993-87-2 - Upstream Downstream Industry

Raw Materials

1H-Pyrrolo[2,3-c]pyridine, 4-bromo-7-chloro-1-[(4-methylphenyl)sulfonyl]-
4-bromo-7-methoxy-1-tosyl-1H-pyrrolo[2,3-c]pyridine
4-bromo-6-methyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
5-Bromo-2-chloro-3-nitropyridine
2-METHOXY-3-NITRO-4-PICOLINE
4-bromo-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one
4-bromo-7-chloro-1H-pyrrolo[2,3-c]pyridine
5-BroMo-4-[2-(diMethylaMino)ethenyl]-2-Methoxy-3-nitropyridine
5-Bromo-2-methoxy-4-methyl-3-nitropyridine
Tosyl chloride
2-Chloro-4-methyl-3-nitropyridine
1,4-Dioxane
Iodomethane

Downstream Products

ABBV-075

1445993-87-2 - Introduction

[2,3-c]pyridin-7(6h)-one is an organic compound with the chemical formula C15H12BrNO2S.

Nature:
-Appearance: This compound is a white solid.
-Melting point: Its melting point range is between 150-155°C.
-Solubility: It can be dissolved in organic solvents, such as dichloromethane, ethanol, acetone, etc., while the solubility in water is low.

Use:
[2,3-c]pyridin-7(6h)-one is commonly used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as biologically active molecules and drugs, such as anti-tumor drugs or antiviral drugs.

Method:
The method of preparing the compound can be carried out by the following steps:
1. First, 1-methyl -2-(m-tosyl) pyrrolo [2,3-c] pyridine is reacted with ethyl bromoacetate, 1-Methyl -2-(m-tosyl)-3-bromopyrrolo [2,3-c] pyridine is obtained.
2. Then, under basic conditions, methyl magnesium bromide is used to react with 1-methyl -2-(m-tosyl)-3-bromopyrrolo [2,3-c] pyridine, the target product [2,3-c]pyridin-7(6h)-one was produced.

Safety Information:
For specific safety information about this compound, including toxicity, hazards, and handling precautions, consult the relevant safety data sheet at the time of use and handle in accordance with proper laboratory procedures. At the same time, pay attention to protective measures during operation, such as wearing protective glasses, gloves and laboratory coats, avoiding skin contact and inhalation.

Last Update：2024-04-09 21:54:55