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13999-39-8

4,5-dimethylisoxazol-3-amine

CAS: 13999-39-8

Molecular Formula: C5H8N2O

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13999-39-8 - Names and Identifiers

Name 4,5-dimethylisoxazol-3-amine
Synonyms azocan-2-one
dimethyl-1,2-oxazol-3-amine
4,5-Dimethylisoxazol-3-amine
4,5-dimethylisoxazol-3-amine
3-Amino-4,5-Dimethylisoxazole
4,5-Dimethyl-3-aminoisoxazole
3-Amino-4,5-dimethylisoxazole
3-amino-4,5-dimethylisoxazole
3-IsoxazolaMine, 4,5-diMethyl-
4,5-dimethyl-1,2-oxazol-3-amine
(4,5-dimethylisoxazol-3-yl)amine
CAS 13999-39-8
EINECS 237-802-7
InChI InChI=1/C5H8N2O/c1-3-4(2)8-7-5(3)6/h1-2H3,(H2,6,7)

13999-39-8 - Physico-chemical Properties

Molecular FormulaC5H8N2O
Molar Mass112.13
Density1.118±0.06 g/cm3(Predicted)
Melting Point115-117 °C
Boling Point250.0±35.0 °C(Predicted)
Flash Point104.981°C
Vapor Presure0.022mmHg at 25°C
pKa2.26±0.10(Predicted)
Storage ConditionKeep in dark place,Sealed in dry,Room Temperature
Refractive Index1.521

13999-39-8 - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk Codes22 - Harmful if swallowed

13999-39-8 - Reference Information

introduction 3-amino -4,5-dimethylisoxazole is gray-white to beige crystalline powder, 3-amino -4,5-dihydroisoxazole is used as the nitrized derivative of isoxazoline, it plays an important role in the preparation of various antibacterial drug molecules.
preparation method dissolve hydroxylamine hydrochloride in 100ml of ethyl acetate to prepare a solution; Dissolve sodium bicarbonate in 100ml of water, add 500ml of ethyl acetate, add nitro-substituted α,β-unsaturated ketone in an ice water bath, and add the prepared hydroxylamine hydrochloride ethyl acetate solution dropwise, the temperature of the dropping process is controlled at 0-8 ℃, after the dropping is finished, the water bath is fully reacted for 2 hours, stirred at room temperature for 3 hours, the organic phase is divided, the anhydrous sodium sulfate is dried, and the pressure is concentrated to obtain 3-Nitro-4, 5-dihydroisoxazole.
Last Update:2024-04-09 21:54:55
13999-39-8
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