138499-08-8

138499-08-8 - Names and Identifiers

Name	(3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE
Synonyms	(3S)-TetrahydrofuranylsuccinMidyl-carbonate (3S)-Tetrahydrofuranylsuccinmidyl-carbonate (3S)-TETRAHYDROFURANYLSUCCINIMIDYL-CARBONATE 3(S)-Hydroxy Tetrahydrofuran, N-HydroxysuccinaMidylcarbonate (S)-2,5-dioxopyrrolidin-1-yl (tetrahydrofuran-3-yl) carbonate (S)-2,5-Dioxopyrrolidin-1-yl (tetrahydrofuran-2-yl) carbonate 1-({[(3S)-tetrahydrofuran-3-yloxy]carbonyl}oxy)pyrrolidine-2,5-dione Carbonic Acid 2,5-Dioxopyrrolidin-1-yl (S)-Tetrahydrofuran-3-yl Ester 1-[[[[(3S)-Tetrahydro-3-furanyl]oxy]carbonyl]oxy]-2,5-pyrrolidinedione Carbonic acid, 2,5-dioxo-1-pyrrolidinyl (3S)-tetrahydro-3-furanyl ester
CAS	138499-08-8
InChI	InChI=1/C9H11NO6/c11-7-1-2-8(12)10(7)16-9(13)15-6-3-4-14-5-6/h6H,1-5H2/t6-/m0/s1

138499-08-8 - Physico-chemical Properties

Molecular Formula	C9H11NO6
Molar Mass	229.19
Density	1.45g/cm³
Melting Point	114-117°C
Boling Point	338.7°C at 760 mmHg
Flash Point	158.7°C
Solubility	Chloroform, Dichloromethane, Ethyl Acetate, Ether, Methanol
Vapor Presure	9.63E-05mmHg at 25°C
Appearance	Solid
Color	Off-White
Storage Condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Refractive Index	1.536

138499-08-8 - Introduction

(S)-Tetrahydrofuranyl succinimidyl carbonate is an organic compound with the chemical formula C10H15NO6. It is a white to pale yellow solid, soluble in some organic solvents, such as ethanol and dichloromethane.

(S)-tetrahydrofuryl succinimidyl carbonate is a chiral compound with good catalytic properties. It is often used as a chiral catalyst to participate in organic synthesis reactions, especially asymmetric synthesis reactions. It can be used to catalyze the hydroxyl esterification of esters, the alcoholysis of esters, and the condensation of amines with aldehydes.

The method for preparing (S)-tetrahydrofuryl succinimidyl carbonate is generally to react (S)-phenylsuccinic acid ester with acetonitrile, followed by imidization to form (S)-N-phenylbromosuccinimidyl ester, which is finally subjected to carbonation to obtain the target product.

Regarding safety information, there is currently no separate report specifically for (S)-tetrahydrofuryl succinimidyl carbonate. However, as a chemical, its use needs to follow general safety practices. During use, personal protective equipment such as protective gloves and goggles should be worn to avoid inhalation of dust or skin contact. When stored, it should be kept in a dry, cool place, away from fire and oxidizing agents. If accidentally splashed into the skin or eyes, rinse immediately with plenty of water and seek medical advice.

Last Update：2024-04-10 22:29:15