1374666-32-6
Mal-PEG2-acid
CAS: 1374666-32-6
Molecular Formula: C11H15NO6
1374666-32-6 - Names and Identifiers
1374666-32-6 - Physico-chemical Properties
| Molecular Formula | C11H15NO6 |
| Molar Mass | 257.24 |
| Density | 1.329±0.06 g/cm3(Predicted) |
| Boling Point | 455.7±35.0 °C(Predicted) |
| pKa | 4.27±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Physical and Chemical Properties | Bioactive Mal-PEG2-acid is a non-cleavable ADC linker used to synthesize antibody-coupled drugs (ADC). Mal-PEG2-acid can be active with Tubulysin (HY-128914) and its cytotoxic derivatives. Mal-PEG2-acid can also be used as PROTAC linker for PROTAC synthesis. |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
1374666-32-6 - Reference Information
| biological activity | Mal-PEG2-acid is a non-cleavable ADC linker used to synthesize antibody-coupled drugs (ADC). Mal-PEG2-acid can be active with Tubulysin (HY-128914) and its cytotoxic derivatives. Mal-PEG2-acid can also be used as PROTAC linker for PROTAC synthesis. |
| target | Non-cleavable PEGs |
| in vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 19:55:45
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CAS: 1374666-32-6
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