1365531-98-1

1365531-98-1 - Names and Identifiers

Name	(R)-2,2''-Bis[bis(4-methoxy-3,5-di-t-butylphenyl)phosphino]-4,4'',6,6''-tetramethoxy)-1,1''-biphenyl
Synonyms	(R)-2,2''-Bis[bis(4-methoxy-3,5-di-t-butyL (R)-2,2'-Bis[bis(4-methoxy-3,5-di-t-butylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl (R)-2,2''-Bis[bis(4-methoxy-3,5-di-t-butylphenyl)phosphino]-4,4'',6,6''-tetramethoxy)-1,1''-biphenyl (R)-2,2'-Bis[bis(4-Methoxy-3,5-di-t-butylphenyl)phosphino]-4,4',6,6'-tetraMethoxybiphenyl (R)-DTBM-Garphos Phosphine, 1,1'-[(1R)-4,4',6,6'-tetramethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-bis[3,5-bis(1,1-dimethylethyl)-4-methoxyphenyl]-
CAS	1365531-98-1

1365531-98-1 - Physico-chemical Properties

Molecular Formula	C76H108O8P2
Molar Mass	1211.61
Boling Point	990.9±65.0 °C(Predicted)
Water Solubility	Insoluble in water.
Appearance	crystal
Color	white
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Air Sensitive

1365531-98-1 - Introduction

(R)-2,2 "-Bis[bis(4-methoxy-3,5-di-t-butylphenyl)phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-biphenyl is an organic compound, often referred to by the abbreviation "BisP-Phos.

Nature:
The compound is a white to pale yellow solid. Its molecular formula is C72H94O6P2 and its relative molecular mass is 1103.26g/mol.

Use:
(R)-2,2 "-Bis[bis(4-methoxy-3, 5-di-tylphenyl) phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-biphenyl is a chiral ligand, often used as a ligand in metal-catalyzed reactions. It can be combined with catalysts to promote and control various organic synthesis reactions, such as asymmetric hydrogenation, asymmetric reduction, asymmetric sequential reactions and the synthesis of reactive carbonyl compounds.

Preparation Method:
The preparation of (R)-2,2 "-Bis[bis(4-methoxy-3,5-di-t-butylphenyl)phosphino]-4,4", 6,6 "-tetramethoxy)-1,1"-biphenyl usually involves a multi-step synthesis. The key step is to connect the two benzene rings with the protecting groups on the tert-butylbenzene ring by nucleophilic substitution reaction in the presence of sodium diphenylphosphonate.

Safety Information:
(R)-2,2 ''-Bis[bis(4-methoxy-3,5-di-t-butylphenyl)phosphino]-4,4'',6,6 ''-tetramethoxy)-1,1''-biphenyl specific safety information has not been fully reported. However, as a general guideline when handling chemicals, use appropriate protective equipment to avoid contact with skin, eyes and inhalation. Before use, it is recommended to read the safety data form provided by its supplier and follow the correct laboratory operating procedures.

Last Update：2024-04-10 22:29:15