1361146-90-8

1361146-90-8 - Names and Identifiers

Name	(3aR,8aR)-(-)-4,4,8,8-Tetrakis (3,5-di-i-propylphenyl)tetrahydro-2,2-diMethyl-6-phenyl-1,3-dioxolo[4,5-e]dioxaphosphepin
Synonyms	(3aR,8aR)-(-)-4,4,8,8-Tetrakis(3,5-di-i-propylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-1,3-dioxolo[4,5-e]dioxaphosphepine (3aR,8aR)-(-)-4,4,8,8-Tetrakis (3,5-di-i-propylphenyl)tetrahydro-2,2-diMethyl-6-phenyl-1,3-dioxolo[4,5-e]dioxaphosphepin (3aR,8aR)-4,4,8,8-Tetrakis(3,5-diisopropylphenyl)-2,2-dimethyl-6-phenyltetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepine (3aR,8aR)-4,4,8,8-Tetrakis[3,5-bis(1-methylethyl)phenyl]tetrahydro-2,2-dimethyl-6-phenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin 1,3-Dioxolo[4,5-e][1,3,2]dioxaphosphepin, 4,4,8,8-tetrakis[3,5-bis(1-methylethyl)phenyl]tetrahydro-2,2-dimethyl-6-phenyl-, (3aR,8aR)-
CAS	1361146-90-8

1361146-90-8 - Physico-chemical Properties

Molecular Formula	C61H82O4P
Molar Mass	910.275141
Boling Point	764.8±60.0 °C(Predicted)
Appearance	Powder
Color	off-white
Storage Condition	2-8 ℃, dark, nitrogen storage

1361146-90-8 - Introduction

(3aR,8aR)-4,4,8,8-tetrakis [3,5-di (isopropyl) phenyl] tetrahydro-2, 2-dimethyl-6-phenyl-1, 3-dioxolo [4,5-e][1,3,2] dioxophos, abbreviated as TDiPP. The following is a description of the nature, use, formulation and safety information of TDiPP:

Nature:
- TDiPP is a crystalline solid with low melting point and high solubility.
-It is an asymmetric molecule, with chirality, and there are two stereoisomers.
- TDiPP has good stability at room temperature.

Use:
- TDiPP is a new type of organic phosphorus reagent, which is one of the representatives of asymmetric chiral cyclic phosphorus reagents.
-It is widely used in metal-catalyzed reactions and can be used as a chiral ligand catalyst to participate in asymmetric catalytic reactions.
- TDiPP can also be used for the synthesis of chiral organic molecules, such as the preparation of chiral drugs and pesticides.

Method:
-The preparation method of TDiPP is generally carried out by a multi-step reaction, the specific steps are as follows:
1. From Di (isopropyl) phenyl magnesium bromide synthesis of Di (isopropyl) phenyl magnesium, and then react with phenylacetylene to obtain DI (isopropyl) phenyl Lithium derivatives of phenylacetylene.
2. React 1,4-diphenyl -1,3-diyne with Di (isopropyl) phenyl lithium to generate the precursor of TDiPP.
3. Finally, TDiPP is generated by cyclization reaction.

Safety Information:
- TDiPP is not currently listed as a particularly toxic or dangerous compound.
-However, as an organic substance, it has certain potential hazards.
-When using and handling TDiPP, follow appropriate laboratory procedures and personal protective measures.
-When handling organophosphorus reagents, care should be taken to avoid direct contact with the skin and inhalation of its dust or vapor.
-If an accident occurs, take appropriate first aid measures immediately and consult a professional for assistance.

Last Update：2024-04-09 21:00:56