134653-98-8

134653-98-8 - Names and Identifiers

Name	3-Pyridinecarboxylicacid, 6-(1,1-dimethylethyl)-1,4-dihydro-4-oxo-, ethyl ester
Synonyms	Ethyl6-(tert-Butyl)-4-hydroxynicotinate 6-tert-butyl-4-oxo-1H-pyridine-3-carboxylic acid ethyl ester Ethyl 6-(tert-butyl)-4-oxo-1,4-dihydropyridine-3-carboxylate 3-Pyridinecarboxylicacid, 6-(1,1-dimethylethyl)-1,4-dihydro-... 6-tert-butyl-1,4-Dihydro-4-oxo-3-pyridinecarboxylic acid ethyl ester 3-Pyridinecarboxylicacid, 6-(1,1-dimethylethyl)-1,4-dihydro-4-oxo-, ethyl ester 3-Pyridinecarboxylicacid, 6-(1,1-diMethylethyl)-1,4-dihydro-4-oxo-, ethyl ester
CAS	134653-98-8

134653-98-8 - Physico-chemical Properties

Molecular Formula	C12H17NO3
Molar Mass	223.27
Density	1.105±0.06 g/cm3(Predicted)
Boling Point	324.8±42.0 °C(Predicted)
pKa	10.09±0.69(Predicted)
Storage Condition	2-8°C

134653-98-8 - Introduction

Ethyl 6-tert-butyl-4-oxo-1, 4-dihydropyridine-3-carboxylate, also known as ethyl tert-butylmatate, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Molecular formula: C13H21NO3
-Molecular weight: 239.31g/mol
-Melting point:-22°C
-Boiling point: 208°C
-Density: 0.993g/cm3
-Solubility: Soluble in organic solvents such as ether and acetone

Use:
-6-tert-butyl-4-oxo-1, 4-dihydropyridine-3-carboxylic acid ethyl ester is a commonly used organic synthesis intermediate, which is widely used in the synthesis of drugs and chemicals. It can be used to synthesize various pesticides, pharmaceutical intermediates and functional materials.

Preparation Method:
The preparation of ethyl 6-tert-butyl-4-oxo-1, 4-dihydropyridine-3-carboxylate can generally be carried out by the following steps:
1.1,4-dihydropyridine raw materials were obtained.
2.1,4-dihydropyridine is reacted with tert-butyl chloroformate, and the condensation reaction is carried out under appropriate solvent and temperature conditions.
3. then the product obtained by the condensation reaction is subjected to oxidative decarboxylation to remove the carboxylic acid group to form 6-tert-butyl -4-oxo -1,4-dihydropyridine -3-carboxylic acid ethyl ester.

Safety Information:
Ethyl -6-tert-butyl-4-oxo-1, 4-dihydropyridine-3-carboxylate may be irritating to the eyes, skin, and respiratory tract.
-Wear appropriate personal protective equipment such as gloves, safety glasses and respiratory protection when used.
-Avoid contact with strong oxidants and keep away from fire sources.
-Store it in a sealed manner and avoid prolonged exposure to the sun.
-If ingested or inhaled, seek medical attention immediately.

Last Update：2024-04-09 02:00:42