13438-65-8
3-Pyridinecarboxamide,2-amino-(9CI)
CAS: 13438-65-8
Molecular Formula: C6H7N3O
13438-65-8 - Names and Identifiers
| Name | 3-Pyridinecarboxamide,2-amino-(9CI) |
| Synonyms | 2-Aminonicotinamide 2-aMino-3-nicotinaMide 2-aMinopyridin-3-carboxaMide 2-Amino-3-pyridinecarboxamide 2-aminopyridine-3-carboxamide 3-Pyridinecarboxamide, 2-amino- 3-Pyridinecarboxamide,2-amino-(9CI) |
| CAS | 13438-65-8 |
| InChI | InChI=1/C6H7N3O/c7-5-4(6(8)10)2-1-3-9-5/h1-3H,(H2,7,9)(H2,8,10) |
13438-65-8 - Physico-chemical Properties
| Molecular Formula | C6H7N3O |
| Molar Mass | 137.14 |
| Density | 1.323±0.06 g/cm3(Predicted) |
| Melting Point | 194-200 °C |
| Boling Point | 328.2±22.0 °C(Predicted) |
| Flash Point | 152.3°C |
| Vapor Presure | 0.000192mmHg at 25°C |
| Appearance | Solid |
| Color | Pale yellow |
| pKa | 14.60±0.50(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.643 |
| MDL | MFCD00128873 |
13438-65-8 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | 6.1 |
13438-65-8 - Introduction
2-Aminonicotinamide is an organic compound with the chemical formula C5H7N3O, also known as niacin. The following is a description of its nature, use, preparation and safety information:
Nature:
2-amino nicotinamide is a solid, the appearance of white crystals or crystalline powder. It has the structure of nicotinamide, in which one hydrogen atom is replaced by an amino group, thus having an amino group. It is soluble in water at room temperature and has good thermal stability. 2-Aminonicotinamide is a form of vitamin B3 and a constituent of the coenzymes NAD and NADP.
Use:
2-amino nicotinamide has a wide range of uses. It is a form of vitamin B3 and can be used as a food and nutritional supplement to maintain health and prevent vitamin B3 deficiency. In addition, it can also be used in the pharmaceutical industry as an intermediate for the synthesis of drugs and certain anticancer drugs. 2-Aminonicotinamide can also be used in the preparation of cosmetics and skin care products due to its antioxidant properties.
Preparation Method:
2-Aminonicotinamide can be prepared by a variety of methods. The most common method is to use the reaction of nicotinamide and ammonia, and the reaction conditions can use a base catalyst. In addition, 2-aminonicotinamide can also be synthesized from a pyridinone compound by a reduction reaction.
Safety Information:
2-Aminonicotinamide is generally safe in normal doses, but high doses may cause some side effects, such as skin flushing and rash. Long-term use of high doses can cause liver and gastrointestinal problems. Before using 2-aminonicotinamide as a supplement or medication, a doctor or professional should be consulted to understand the appropriate dosage and potential risks. When storing and handling 2-aminonicotinamide, chemical safety measures should be observed to avoid inhalation, contact with the skin, or entry into the digestive tract.
Nature:
2-amino nicotinamide is a solid, the appearance of white crystals or crystalline powder. It has the structure of nicotinamide, in which one hydrogen atom is replaced by an amino group, thus having an amino group. It is soluble in water at room temperature and has good thermal stability. 2-Aminonicotinamide is a form of vitamin B3 and a constituent of the coenzymes NAD and NADP.
Use:
2-amino nicotinamide has a wide range of uses. It is a form of vitamin B3 and can be used as a food and nutritional supplement to maintain health and prevent vitamin B3 deficiency. In addition, it can also be used in the pharmaceutical industry as an intermediate for the synthesis of drugs and certain anticancer drugs. 2-Aminonicotinamide can also be used in the preparation of cosmetics and skin care products due to its antioxidant properties.
Preparation Method:
2-Aminonicotinamide can be prepared by a variety of methods. The most common method is to use the reaction of nicotinamide and ammonia, and the reaction conditions can use a base catalyst. In addition, 2-aminonicotinamide can also be synthesized from a pyridinone compound by a reduction reaction.
Safety Information:
2-Aminonicotinamide is generally safe in normal doses, but high doses may cause some side effects, such as skin flushing and rash. Long-term use of high doses can cause liver and gastrointestinal problems. Before using 2-aminonicotinamide as a supplement or medication, a doctor or professional should be consulted to understand the appropriate dosage and potential risks. When storing and handling 2-aminonicotinamide, chemical safety measures should be observed to avoid inhalation, contact with the skin, or entry into the digestive tract.
Last Update：2024-04-09 20:49:11
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View History
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