132463-02-6

132463-02-6 - Names and Identifiers

Name	Diethyl N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-methylamino]-2-thenoyl]-L-glutamate
Synonyms	DiethylN- 5- N- (3,4-dihydro-2-Methyl-4-oxy-... Diethyl N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)... DiethylN-[5-[N-[(3,4-dihydro-2-methyl-4-oxy-6-quinazolinyl)methyl]-N-methylamino]-2-thenoyl]-L-glutamate Diethyl N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]-N-methylamino]-2-thenoyl]-L-glutamate N-[[5-[[(3,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-L-glutamic acid 1,5-diethyl ester L-Glutamic acid, N-[[5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-, 1,5-diethyl ester
CAS	132463-02-6
InChI	InChI=1/C25H30N4O6S/c1-5-34-22(30)12-9-19(25(33)35-6-2)28-24(32)20-10-11-21(36-20)29(4)14-16-7-8-18-17(13-16)23(31)27-15(3)26-18/h7-8,10-11,13,19H,5-6,9,12,14H2,1-4H3,(H,28,32)(H,26,27,31)/t19-/m0/s1

132463-02-6 - Physico-chemical Properties

Molecular Formula	C25H30N4O6S
Molar Mass	514.59
Density	1.32
pKa	13.09±0.46(Predicted)
Refractive Index	1.623

132463-02-6 - Introduction

N-[5-[N-[(3,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl) methyl]-N-methylamino]-2-thiophenecarboxyl]-L-glutamic acid diethyl ester is an organic compound. The following is a brief summary of the properties, use, preparation and safety information of the compound:

Nature:
-Appearance: Usually solid, may be white to white crystals or powder.
-Molecular formula: C26H33N5O4S
-Molecular weight: 515.65g/mol
-Melting point: about 165-170°C
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and chloroform.

Use:
- N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl) methyl]-N-methylamino]-2-thienoyl]-L-glutamic acid diethyl ester is used in the pharmaceutical field as an enzyme inhibitor, in particular as a tyrosine kinase inhibiting compound.
-In the laboratory, it is also used to study protein function and metabolism.

Preparation Method:
-The specific synthesis method of this compound may be complicated, involving multi-step reactions and special reagents. Specific preparation methods can be found in the relevant scientific literature or patents.

Safety Information:
- N-[5-[N-[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl) methyl]-N-methylamino]-2-thienoyl]-L-The safety and toxicity of glutamic acid diethyl ester have not been fully studied, so it needs to be used with caution.
-Standard laboratory safety procedures should be followed when handling this compound.
-The compound needs to be stored and handled properly to avoid contact with flammable substances.

Please note that the above information only provides an overview of the compound and more detailed literature and expert opinion may be required for specific properties, uses, preparation and safety information.

Last Update：2024-04-09 20:49:11