131747-65-4
6-Trifluoromethyl-pyridine-2-carbaldehyde
CAS: 131747-65-4
Molecular Formula: C7H4F3NO
131747-65-4 - Names and Identifiers
131747-65-4 - Physico-chemical Properties
| Molecular Formula | C7H4F3NO |
| Molar Mass | 175.11 |
| Density | 1.369±0.06 g/cm3(Predicted) |
| Boling Point | 168.7±35.0 °C(Predicted) |
| Flash Point | 75℃ |
| Vapor Presure | 1.6mmHg at 25°C |
| Appearance | powder or crystals |
| pKa | 1.06±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.476 |
131747-65-4 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
131747-65-4 - Introduction
6-Trifluoromethyl-2-aldehyde pyridine is an organic compound with the chemical formula C7H4F3NO. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless or yellowish crystal
-Melting point: about 68-71 degrees Celsius
-Solubility: Soluble in many organic solvents such as alcohols, ethers and esters
-Stability: relatively stable at room temperature, but sensitive to light and heat
Use:
-6-Trifluoromethyl-2-aldehyde pyridine can be used as an organic synthesis intermediate, which is widely used in the synthesis of drugs, pesticides and functional materials.
-It has important application value in the synthesis of heterocyclic structures and fluorine-containing organic compounds.
Preparation Method:
-6-Trifluoromethyl-2-aldehyde pyridine is generally obtained by reacting pyridine with trifluoroacetic anhydride. The pyridine and trifluoroacetic anhydride are first mixed and heated to the reaction temperature. Subsequently, the product was purified by distillation and crystallization under reduced pressure.
Safety Information:
-6-Trifluoromethyl-2-aldehyde pyridine is irritating to a certain extent. Direct contact with skin and eyes should be avoided, and inhalation of its vapor and dust should be avoided. During operation, wear appropriate protective equipment such as safety glasses, gloves, etc.
-According to the United States Environmental Protection Agency, the compound is classified as a "suspicious and unclassified poison" in environmental terms ".
-When storing and handling the compound, comply with the requirements for safe storage and handling of chemicals, properly manage waste, and comply with relevant regulations and guidelines.
-Further information and detailed operating instructions can be obtained through the Safety Data Sheet (SDS).
Nature:
-Appearance: colorless or yellowish crystal
-Melting point: about 68-71 degrees Celsius
-Solubility: Soluble in many organic solvents such as alcohols, ethers and esters
-Stability: relatively stable at room temperature, but sensitive to light and heat
Use:
-6-Trifluoromethyl-2-aldehyde pyridine can be used as an organic synthesis intermediate, which is widely used in the synthesis of drugs, pesticides and functional materials.
-It has important application value in the synthesis of heterocyclic structures and fluorine-containing organic compounds.
Preparation Method:
-6-Trifluoromethyl-2-aldehyde pyridine is generally obtained by reacting pyridine with trifluoroacetic anhydride. The pyridine and trifluoroacetic anhydride are first mixed and heated to the reaction temperature. Subsequently, the product was purified by distillation and crystallization under reduced pressure.
Safety Information:
-6-Trifluoromethyl-2-aldehyde pyridine is irritating to a certain extent. Direct contact with skin and eyes should be avoided, and inhalation of its vapor and dust should be avoided. During operation, wear appropriate protective equipment such as safety glasses, gloves, etc.
-According to the United States Environmental Protection Agency, the compound is classified as a "suspicious and unclassified poison" in environmental terms ".
-When storing and handling the compound, comply with the requirements for safe storage and handling of chemicals, properly manage waste, and comply with relevant regulations and guidelines.
-Further information and detailed operating instructions can be obtained through the Safety Data Sheet (SDS).
Last Update：2024-04-09 02:00:41
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View History
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