124988-44-9
Ethyl (R)-2-azido-propionate
CAS: 124988-44-9
Molecular Formula: C5H9N3O2
124988-44-9 - Names and Identifiers
| Name | Ethyl (R)-2-azido-propionate |
| Synonyms | (R)-ETHYL 2-AZIDOPROPANOATE Ethyl (R)-2-azido-propionate Propanoic acid, 2-azido-, ethyl ester, (2R)- |
| CAS | 124988-44-9 |
124988-44-9 - Physico-chemical Properties
| Molecular Formula | C5H9N3O2 |
124988-44-9 - Introduction
Ethyl (R)-2-azidopropionate is a chemical compound with the formula:
CH3OC(O)CH(N=N)CH3
Nature:
Ethyl (R)-2-azidopropionate is a colorless liquid with a distinctive odor. It has a boiling point of about 143°C and a density of 1.05g/cm3. At room temperature, it is stable.
Use:
Ethyl (R)-2-azidopropionate has certain application value in the field of organic synthesis. It can be used as a catalyst, ligand or as an intermediate for fine chemicals. It has good chiral induction properties in asymmetric synthesis and can be used to synthesize various chiral compounds.
Method:
Ethyl (R)-2-azidopropionate can be prepared by the following procedure. First, ethyl acetate is reacted with diisopropylamine in an appropriate solvent to produce ethyl 2-azidopropionate. Then, by enantioselective reduction of the chiral compound, ethyl (R)-2-azidopropionate is obtained.
Safety Information:
Ethyl (R)-2-azidopropionate is dangerous to a certain extent, and safety should be paid attention to when using it. It may cause irritation to the skin, eyes and respiratory system. During the operation, appropriate personal protective equipment should be worn, such as gloves, protective glasses and protective masks, avoid contact with skin and eyes, and pay attention to good ventilation. If inhaled, ingested, or exposed to this compound, seek medical attention.
CH3OC(O)CH(N=N)CH3
Nature:
Ethyl (R)-2-azidopropionate is a colorless liquid with a distinctive odor. It has a boiling point of about 143°C and a density of 1.05g/cm3. At room temperature, it is stable.
Use:
Ethyl (R)-2-azidopropionate has certain application value in the field of organic synthesis. It can be used as a catalyst, ligand or as an intermediate for fine chemicals. It has good chiral induction properties in asymmetric synthesis and can be used to synthesize various chiral compounds.
Method:
Ethyl (R)-2-azidopropionate can be prepared by the following procedure. First, ethyl acetate is reacted with diisopropylamine in an appropriate solvent to produce ethyl 2-azidopropionate. Then, by enantioselective reduction of the chiral compound, ethyl (R)-2-azidopropionate is obtained.
Safety Information:
Ethyl (R)-2-azidopropionate is dangerous to a certain extent, and safety should be paid attention to when using it. It may cause irritation to the skin, eyes and respiratory system. During the operation, appropriate personal protective equipment should be worn, such as gloves, protective glasses and protective masks, avoid contact with skin and eyes, and pay attention to good ventilation. If inhaled, ingested, or exposed to this compound, seek medical attention.
Last Update：2024-04-09 21:01:54
