| Molecular Formula | C27H32F2N8.CH4O3S |
| Molar Mass | 602.7 |
| Solubility | Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml). |
| Appearance | solid |
| Color | Off-white |
| Storage Condition | -20℃ |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. |
| Physical and Chemical Properties | Bioactive Abemaciclib (LY2835219) is a potent, selective CDK4 and CDK6 inhibitor with an IC50 of 2 nM and 10 nM, respectively, in a cell-free assay. Phase 3. |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 1.659 ml | 8.296 ml | 16.592 ml |
| 5 mM | 0.332 ml | 1.659 ml | 3.318 ml |
| 10 mM | 0.166 ml | 0.83 ml | 1.659 ml |
| 5 mM | 0.033 ml | 0.166 ml | 0.332 ml |