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1231930-82-7

2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimida

CAS: 1231930-82-7

Molecular Formula: C27H32F2N8.CH4O3S

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1231930-82-7 - Names and Identifiers

Name 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimida
Synonyms LY2835219
Bemaciclib(salt)
LY2835219 mesylate
LY2835219 Ms salt, Abemaciclib Ms salt
2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimida
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate
CAS 1231930-82-7

1231930-82-7 - Physico-chemical Properties

Molecular FormulaC27H32F2N8.CH4O3S
Molar Mass602.7
Solubility Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).
Appearancesolid
ColorOff-white
Storage Condition-20℃
StabilityStable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Physical and Chemical PropertiesBioactive Abemaciclib (LY2835219) is a potent, selective CDK4 and CDK6 inhibitor with an IC50 of 2 nM and 10 nM, respectively, in a cell-free assay. Phase 3.

1231930-82-7 - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.659 ml8.296 ml16.592 ml
5 mM0.332 ml1.659 ml3.318 ml
10 mM0.166 ml0.83 ml1.659 ml
5 mM0.033 ml0.166 ml0.332 ml
Last Update:2024-01-02 23:10:35
1231930-82-7
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Product Name: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate Visit Supplier Webpage Request for quotation
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Product Name: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate Visit Supplier Webpage Request for quotation
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View History
1231930-82-7
光纤用硅油混合剂
间碘苯甲醇
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2-Amine-5-Fluorothiazol HCL
苯甲醯丙酮
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