1218935-59-1
(2R)-2-(2,5-DIFLUOROPHENYL)PYRROLIDINE
CAS: 1218935-59-1
Molecular Formula: C10H11F2N
1218935-59-1 - Names and Identifiers
1218935-59-1 - Physico-chemical Properties
| Molecular Formula | C10H11F2N |
| Molar Mass | 183.2 |
| Density | 1.164±0.06 g/cm3(Predicted) |
| Boling Point | 213.5±40.0 °C(Predicted) |
| pKa | 9.02±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Use | Uses 2-(2, 5-difluorophenyl) pyrrolidine is used in the synthesis of imidazoles [1,2-b] pyrazines and as Trk kinase inhibitors. |
1218935-59-1 - Upstream Downstream Industry
1218935-59-1 - Introduction
(2R)-2-(2,5-difluorophenyl) PYRROLIDINE, also known as (2R)-(2R)-2-(2,5-difluorophenyl) PYRROLIDINE, is an organic compound. It has the chemical formula C11H12F2N and has one chiral center.
(2R)-2-(2,5-difluorophenyl) PYRROLIDINE is mainly used as a pharmaceutical intermediate and has important applications in the synthesis of pharmaceutical compounds. It is widely used in the pharmaceutical field for the synthesis of antipsychotic, especially antischizophrenic, drugs. In addition, it is used as an intermediate for pesticides and insecticides in the agricultural sector.
The preparation of (2R)-2-(2,5-difluorophenyl) PYRROLIDINE can be obtained by the reaction of styrene and fluorine gas. In the reaction, (2R)-2-(2,5-difluorophenyl) PYRROLIDINE is generated by fluorination of styrene with fluorine gas in the presence of a catalyst and an active oxidant.
With regard to safety information, there is currently no report on the specific danger of (2R)-2-(2,5-difluorophenyl) PYRROLIDINE. However, since it is an organic compound, attention should be paid to correct handling and storage methods when using it, and avoid contact with skin, eyes and other sensitive areas. At the same time, the synthesis and handling of the compound should follow the relevant laboratory safety practices to ensure safety and the effectiveness of protective measures.
(2R)-2-(2,5-difluorophenyl) PYRROLIDINE is mainly used as a pharmaceutical intermediate and has important applications in the synthesis of pharmaceutical compounds. It is widely used in the pharmaceutical field for the synthesis of antipsychotic, especially antischizophrenic, drugs. In addition, it is used as an intermediate for pesticides and insecticides in the agricultural sector.
The preparation of (2R)-2-(2,5-difluorophenyl) PYRROLIDINE can be obtained by the reaction of styrene and fluorine gas. In the reaction, (2R)-2-(2,5-difluorophenyl) PYRROLIDINE is generated by fluorination of styrene with fluorine gas in the presence of a catalyst and an active oxidant.
With regard to safety information, there is currently no report on the specific danger of (2R)-2-(2,5-difluorophenyl) PYRROLIDINE. However, since it is an organic compound, attention should be paid to correct handling and storage methods when using it, and avoid contact with skin, eyes and other sensitive areas. At the same time, the synthesis and handling of the compound should follow the relevant laboratory safety practices to ensure safety and the effectiveness of protective measures.
Last Update：2024-04-09 21:11:58
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View History
1218935-59-1
2,3,4-Trihydrooxy Benzaldehyde
(2-羟乙基)三甲基氯化铵
4-溴代巴豆酸酯
Ac-dA 亚磷酰胺单体
α-苯乙酰乙腈
5-二羟基联苯
二甘醇单甲醚
2-苯乙基乙酸酯
2,3,4-Trihydrooxy Benzaldehyde
(2-羟乙基)三甲基氯化铵
4-溴代巴豆酸酯
Ac-dA 亚磷酰胺单体
α-苯乙酰乙腈
5-二羟基联苯
二甘醇单甲醚
2-苯乙基乙酸酯
Raw Materials for 1218935-59-1
5-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole
Pyrrolidine, 2-(2,5-difluorophenyl)-1-[(S)-(1,1-dimethylethyl)sulfinyl]-, (2R)-
(R)-tert-butyl 2-(2,5-difluorophenyl)pyrrolidine-1-carboxylate
Pyrrolidine, 2-(2,5-difluorophenyl)-1-[(S)-(1,1-dimethylethyl)sulfinyl]-, (2R)-
(R)-tert-butyl 2-(2,5-difluorophenyl)pyrrolidine-1-carboxylate
Downstream Products for 1218935-59-1