120737-59-9
4-N-Boc-2-Methyl-piperazine
CAS: 120737-59-9
Molecular Formula: C10H20N2O2
120737-59-9 - Names and Identifiers
120737-59-9 - Physico-chemical Properties
| Molecular Formula | C10H20N2O2 |
| Molar Mass | 200.28 |
| Density | 0.997±0.06 g/cm3(Predicted) |
| Boling Point | 268.7±15.0 °C(Predicted) |
| Flash Point | 116.3°C |
| Solubility | Chloroform, DMSO, Ethyl Acetate |
| Vapor Presure | 0.00755mmHg at 25°C |
| Appearance | Crystalline powder |
| Color | Clear Colourless |
| pKa | 8.52±0.40(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.459 |
| MDL | MFCD03001706 |
120737-59-9 - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R50 - Very Toxic to aquatic organisms |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S37 - Wear suitable gloves. |
| UN IDs | UN3077 |
| HS Code | 29335990 |
120737-59-9 - Introduction
4-tert-butoxycarbonyl-2-methylpiperazine is an organic compound with the chemical formula C12H21N2O2. It is a white solid with a special smell.
The main use of this compound is as an intermediate in the pharmaceutical field. It can be used to synthesize antihypertensive drugs (such as lodediconol) and anti-allergic drugs (such as acandilin). In addition, it is also widely used in the study of organic synthesis and medicinal chemistry.
The preparation method of 4-tert-butoxycarbonyl-2-methylpiperazine is relatively simple. It can be obtained by reacting tert-butanol with 2-methylpiperazine under acid catalysis. First, tert-butanol is dissolved in an organic solvent under nitrogen, and then 2-methylpiperazine is added. Next, the reaction mixture is heated under acid catalysis, and after the reaction, the generated acid is neutralized by alkali treatment, and then the target product is extracted and purified by crystallization.
When using and storing 4-tert-butoxycarbonyl-2-methylpiperazine, you need to pay attention to safety matters. It is a flammable material and should be kept away from fire and high temperature. At the same time, avoid contact with oxidants and strong acids to prevent dangerous reactions. Wear appropriate protective equipment such as goggles and gloves during operation. If the compound is ingested or inhaled, seek medical attention.
The main use of this compound is as an intermediate in the pharmaceutical field. It can be used to synthesize antihypertensive drugs (such as lodediconol) and anti-allergic drugs (such as acandilin). In addition, it is also widely used in the study of organic synthesis and medicinal chemistry.
The preparation method of 4-tert-butoxycarbonyl-2-methylpiperazine is relatively simple. It can be obtained by reacting tert-butanol with 2-methylpiperazine under acid catalysis. First, tert-butanol is dissolved in an organic solvent under nitrogen, and then 2-methylpiperazine is added. Next, the reaction mixture is heated under acid catalysis, and after the reaction, the generated acid is neutralized by alkali treatment, and then the target product is extracted and purified by crystallization.
When using and storing 4-tert-butoxycarbonyl-2-methylpiperazine, you need to pay attention to safety matters. It is a flammable material and should be kept away from fire and high temperature. At the same time, avoid contact with oxidants and strong acids to prevent dangerous reactions. Wear appropriate protective equipment such as goggles and gloves during operation. If the compound is ingested or inhaled, seek medical attention.
Last Update：2024-04-09 21:11:58
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View History
120737-59-9
阿莫罗芬
52356-01-1
盐酸酚苄明
3-ACETYLBENZOFLUORIDE
2140871-41-4
1354940-68-3
ALDEHYDE C2
1159826-67-1
Calcium nitrate, 4-hydrate
阿莫罗芬
52356-01-1
盐酸酚苄明
3-ACETYLBENZOFLUORIDE
2140871-41-4
1354940-68-3
ALDEHYDE C2
1159826-67-1
Calcium nitrate, 4-hydrate