120034-05-1

120034-05-1 - Names and Identifiers

Name	METHYL 5-BROMO-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLATE
Synonyms	METHYL 5-BROMO-2-HYDROXYNICOTINATE 5-BROMO-3-METHOXYCARBONYL-2(1H)-PYRIDINONE 5-Bromo-2-hydroxynicotinic acid methyl ester METHYL 5-BROMO-2-HYDROXYPYRIDINE-3-CARBOXYLATE methyl5-bromo-2-oxo-1,2-dihydro-3-pyridinecarboxy METHYL 5-BROMO-1,2-DIHYDRO-2-OXO-3-PYRIDINECARBOXYLATE methyl 5-bromo-2-oxo-1,2-dihydropyridine-3-carboxylate METHYL 5-BROMO-2-OXO-1,2-DIHYDRO-3-PYRIDINECARBOXYLATE
CAS	120034-05-1
InChI	InChI=1/C7H6BrNO3/c1-12-7(11)5-2-4(8)3-9-6(5)10/h2-3H,1H3,(H,9,10)

120034-05-1 - Physico-chemical Properties

Molecular Formula	C7H6BrNO3
Molar Mass	232.03
Density	1.737±0.06 g/cm3(Predicted)
Melting Point	181-183°C
Boling Point	346.4±42.0 °C(Predicted)
Flash Point	163.3°C
Vapor Presure	5.76E-05mmHg at 25°C
pKa	8.01±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.58
Physical and Chemical Properties	Storage Conditions: Keep Cold

120034-05-1 - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

120034-05-1 - Introduction

Methyl 5-bromo-2-hydroxynicotinate is an organic compound with the chemical formula C8H6BrNO4.

Nature:
5-bromo-2-hydroxynicotinic acid methyl ester is a white crystalline solid with a special aroma. It is easily soluble in ethanol, chloroform and ether at room temperature, and hardly soluble in water.

Use:
5-Bromo-2-hydroxynicotinic acid methyl ester is commonly used as a pharmaceutical intermediate and can be used to synthesize some drugs, such as the tuberculosis drug isoniazid. It can also be used as a raw material for dyes and pigments.

Preparation Method:
Methyl 5-bromo-2-hydroxynicotinate can be obtained by reacting methyl 2-hydroxynicotinate with bromine under alkaline conditions. The specific reaction conditions can be adjusted according to actual needs.

Safety Information:
Methyl 5-bromo-2-hydroxynicotinate is an organic bromide and may be irritating to the skin, eyes and respiratory tract. Therefore, personal protective measures should be taken during use or handling, such as wearing chemical protective glasses, gloves and breathing apparatus. In the process of storage and transportation, it is necessary to strictly follow the relevant safety operation specifications, avoid contact with combustibles and oxidants, and prevent the risk of fire and explosion.

Last Update：2024-04-09 20:48:19