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117047-07-1

3'- Methoxy Puerarin

CAS: 117047-07-1

Molecular Formula: C22H22O10

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117047-07-1 - Names and Identifiers

Name 3'- Methoxy Puerarin
Synonyms 3''-METHOXYPUERARIN
Puerariaglycoside 3
Methoxypuerarin, 3'-
3'- Methoxy Puerarin
4H-1-Benzopyran-4-one,8-b-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-
4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-
8-beta-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
CAS 117047-07-1

117047-07-1 - Physico-chemical Properties

Molecular FormulaC22H22O10
Molar Mass446.4
Density1.583
Melting Point212-213℃
Boling Point706.0±60.0 °C(Predicted)
Specific Rotation(α)+16.5 (c, 0.2 in DMSO)
Solubility Soluble in methanol
AppearancePowder
pKa6.30±0.20(Predicted)
Storage Condition2-8℃
MDLMFCD21363095
In vivo study 3'-Methoxypuerarin increases the number of surviving neurons in the hippocampal CA1 region and markedly reduces the number of apoptotic pyramidal neurons after ischemia/reperfusion injury. 3'-Methoxypuerarin can protect hippocampal neurons against I/R injury by inhibiting apoptosis.

117047-07-1 - Reference

Reference
Show more
1. Yu, Yunru, et al. "Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases." Chinese medicine 16.1 (2021): 1-14.
2. [IF=3.361] Hongguang Zhang et al."Extraction of isoflavones from Puerariae lobata using subcritical water."Rsc Adv. 2018 Jun;8(40):22652-22658
3. [IF=7.132] Li Yang et al."Supercritical extraction and antioxidant activity of major ingredients in Puerariae lobatae root, Pinus massoniana needle, Citrus reticulata peel and their mixture."J Co2 Util. 2021 Jun;48:101518
4. [IF=5.455] Yu Yunru et al."Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases."Chin Med-Uk. 2021 Dec;16(1):1-14
5. [IF=4.759] Wenjie Wu et al."An analytical strategy for accurate, rapid and sensitive quantitative analysis of isoflavones in traditional Chinese medicines using ultra-high performance supercritical fluid chromatography: Take Radix Puerariae as an example."J Chromato
6. [IF=3.512] Yan Cheng et al."Comparison of the Extraction Efficiency of Isoflavone Compounds from Puerariae lobatae by Ionic Liquids with 11 Anions and 8 Imidazolium-Based Cations."Acs Omega. 2020;5(15):8962–8971

117047-07-1 - Introduction

3 '- Methoxy Puerarin is a chemical substance, also known as Methoxy Pueraria monomer (3'-methoxypterostilbene). It is a compound that occurs naturally in some plants, especially Pueraria.

3 '- Methoxy Puerarin has antioxidant, anti-inflammatory and antibacterial activities. In recent years, it has also been found to have anti-tumor and anti-aging potential. Some studies suggest that it may have a protective effect against cardiovascular disease, cancer and neurodegenerative diseases.

The preparation of 3 '- Methoxy Puerarin is usually carried out by chemical synthesis. This involves a series of reactions, including methoxylation and structural modification of puerarin.

Regarding safety information, although 3 '- Methoxy Puerarin has shown certain pharmacological activities in laboratory studies, further research is needed on its long-term use and dose safety. For the general population, there are no clear recommendations for safe doses. Therefore, before using 3 '- Methoxy Puerarin, it is best to consult the advice of a doctor or professional.
Last Update:2024-04-09 20:02:46
117047-07-1
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CAS: 117047-07-1
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