116384-53-3

116384-53-3 - Names and Identifiers

Name	[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester
Synonyms	Adefovir Dipivoxil InterMediates 9-[2-(DIETHYLPHOSPHONOMETHOXY)ETHYL]ADENINE 9-[2-(diethoxyphosphorylmethoxy)ethyl]purin-6-amine 9-[2-(Diethylphosphonomethoxy)ethyl]adenine(Diethyl PMEA) 9-[2-(diethylphosphonomethoxy)ethyl]adenine phosphonic acid Diethyl [[2-(6-AMino-9H-purin-9-yl)ethoxy]Methyl]phosphonate Diethyl [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonate 9-[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]phosphonicaciddiethylester [[2-(6-AMINO-9H-PURIN-9-YL)ETHOXY]METHYL]PHOSPHONIC ACID DIETHYL ESTER [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester [[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]phosphonic acid diethyl ester(A3)
CAS	116384-53-3
EINECS	601-426-5
InChI	InChI=1/C12H20N5O4P/c1-3-20-22(18,21-4-2)9-19-6-5-17-8-16-10-11(13)14-7-15-12(10)17/h7-8H,3-6,9H2,1-2H3,(H2,13,14,15)
InChIKey	SACBMARVYGBCAK-UHFFFAOYSA-N

116384-53-3 - Physico-chemical Properties

Molecular Formula	C12H20N5O4P
Molar Mass	329.29
Density	1.45±0.1 g/cm3(Predicted)
Melting Point	134.0 to 138.0 °C
Boling Point	531.1±60.0 °C(Predicted)
Flash Point	275°C
Vapor Presure	2.32E-11mmHg at 25°C
pKa	4.18±0.10(Predicted)
Storage Condition	2-8℃
Refractive Index	1.619

116384-53-3 - Introduction

Diethyl [[2-(6-amino-9H-purin-9-yl) ethoxy] methyl] phosphonate, also known as AMPP-EE, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless liquid
-Molecular formula: C14H19N5O6P
-Molecular weight: 413.30g/mol
-Solubility: Soluble in organic solvents such as ethanol and chloroform

Use:
- [2-(6-amino-9H-purin-9-yl) ethoxy] methyl phosphonic acid diethyl ester is commonly used as an important intermediate in the field of biomedicine, and can be used for the synthesis of anti-tumor, anti-virus and anti-inflammatory drugs.

Method:
Diethyl- [2-(6-amino-9H-purin-9-yl) ethoxy] methylphosphonate is typically prepared by chemical synthetic methods. Specific steps involve the use of reaction conditions and catalysts, as well as a series of reaction processes. These methods are generally used only in laboratories or in industry.

Safety Information:
- [2-(6-amino-9H-purin-9-yl) ethoxy] methyl phosphonic acid diethyl ester needs to be safe during use and storage. It can be irritating to the eyes and skin, so wear appropriate personal protective equipment. Avoid inhalation or contact and seek medical advice immediately if maladjustment occurs. In the process of use, should follow the relevant chemical safety procedures.

Last Update：2024-04-09 20:49:11