1153949-11-1
tert-Butyl 3-(cyanomethylene)azetidine-1-carboxylate
CAS: 1153949-11-1
Molecular Formula: C10H14N2O2
1153949-11-1 - Names and Identifiers
1153949-11-1 - Physico-chemical Properties
| Molecular Formula | C10H14N2O2 |
| Molar Mass | 194.23 |
| Density | 1.215 |
| Boling Point | 309.7±35.0 °C(Predicted) |
| Appearance | powder to crystal |
| Color | White to Orange to Green |
| pKa | -1.88±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
1153949-11-1 - Risk and Safety
| UN IDs | UN 3439 6.1/PG III |
| Hazard Class | 6.1 |
| Packing Group | III |
1153949-11-1 - Introduction
3-(Cyanomethylene) azetidine-l-carboxylic acid tert-butyl ester (abbreviation CN,CAS number: 87674-68-8) is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless to slightly yellow liquid
-Molecular formula: C9H15NO2
-Molecular weight: 169.22g/mol
-Melting point:-20°C
-Boiling Point: 145-147°C
-Density: 0.998g/cm3
-refractive index: 1.459-1.461
Use:
CN is often used as an intermediate in fine organic synthesis and has high reactivity. It can be used to synthesize a variety of organic compounds, such as pharmaceutical intermediates, dyes and pesticides.
Method:
A commonly used method for preparing CN is obtained by reacting hydrogen cyanide and 2-methoxycyclobutanyl bromide, and then esterifying with a substrate. Specific steps are as follows:
1. 2-methoxycyclobutane bromide (C9H17BrO) was reacted with sodium cyanide (NaCN) to obtain 2-methoxycyclobutane cyanide (C9H16NOCN).
2. Cyanide 2-methoxycyclobutane was reacted with tert-butanol (C4H10O) to obtain CN.
Safety Information:
CN is a flammable liquid, so avoid fire during storage and operation. Contact with skin can cause irritation, should wear appropriate protective equipment. Avoid inhaling vapors and operate in a well-ventilated area. If inhaled or exposed, call your doctor immediately and provide the relevant chemical information.
Nature:
-Appearance: colorless to slightly yellow liquid
-Molecular formula: C9H15NO2
-Molecular weight: 169.22g/mol
-Melting point:-20°C
-Boiling Point: 145-147°C
-Density: 0.998g/cm3
-refractive index: 1.459-1.461
Use:
CN is often used as an intermediate in fine organic synthesis and has high reactivity. It can be used to synthesize a variety of organic compounds, such as pharmaceutical intermediates, dyes and pesticides.
Method:
A commonly used method for preparing CN is obtained by reacting hydrogen cyanide and 2-methoxycyclobutanyl bromide, and then esterifying with a substrate. Specific steps are as follows:
1. 2-methoxycyclobutane bromide (C9H17BrO) was reacted with sodium cyanide (NaCN) to obtain 2-methoxycyclobutane cyanide (C9H16NOCN).
2. Cyanide 2-methoxycyclobutane was reacted with tert-butanol (C4H10O) to obtain CN.
Safety Information:
CN is a flammable liquid, so avoid fire during storage and operation. Contact with skin can cause irritation, should wear appropriate protective equipment. Avoid inhaling vapors and operate in a well-ventilated area. If inhaled or exposed, call your doctor immediately and provide the relevant chemical information.
Last Update：2024-04-09 02:00:41
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View History
1153949-11-1
1086394-81-1
bariumzirconium(iv)oxide
2-hydroxy-benzoicacibutylester
磷酸一钠单水合物
5-溴-2-甲基吲哚
(环己基甲基)三氯硅烷
3-氯丙环乙烯缩醛
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2-(氨基氧基)乙酸
1086394-81-1
bariumzirconium(iv)oxide
2-hydroxy-benzoicacibutylester
磷酸一钠单水合物
5-溴-2-甲基吲哚
(环己基甲基)三氯硅烷
3-氯丙环乙烯缩醛
(-)-bebeerine
2-(氨基氧基)乙酸