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114903-31-0

Boc-5-Chloro-D-tryptophan

CAS: 114903-31-0

Molecular Formula: C16H19ClN2O4

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114903-31-0 - Names and Identifiers

Name Boc-5-Chloro-D-tryptophan
Synonyms Boc-D-Trp(5-Cl)-OH
Boc-D-5-ChloroTryptophan
BOC-5-CHLORO-D-TRYPTOPHAN
Boc-5-Chloro-D-tryptophan
L-N-Boc-5-chlorotryptophan
(S)-N-Boc-5-chlorotryptophan
D-Tryptophan, 5-chloro-N-[(1,1-dimethylethoxy)carbonyl]-
(R)-2-(N-(Tert-Butoxy)Carbonyl Amino)-3-(5-chloroindol-3-yl)propanoic acid
(R)-2-((tert-Butoxycarbonyl)amino)-3-(5-chloro-1H-indol-3-yl)propanoic acid
CAS 114903-31-0

114903-31-0 - Physico-chemical Properties

Molecular FormulaC16H19ClN2O4
Molar Mass338.79
Density1.338±0.06 g/cm3(Predicted)
Boling Point560.8±50.0 °C(Predicted)
pKa3.82±0.10(Predicted)

114903-31-0 - Introduction

BOC-5-chloro-D-tryptophan, full name N-(tert-butoxycarbonyl)-5-chloro-D-tryptophan, is an organic compound. Its properties and uses are as follows:

Nature:
BOC-5-chloro-D-tryptophan is a colorless solid with a high melting and boiling point. It often forms a clear solution when dissolved in an organic solvent. This compound is relatively stable to air and moisture, but decomposes at high temperatures.

Use:
BOC-5-chloro-D-tryptophan is commonly used in the synthesis of amino protecting reagents and amino acid derivatives in organic synthesis. It can effectively protect the amino functional group, play a protective role in the reaction, to prevent unnecessary side reactions. In addition, BOC-5-chloro-D-tryptophan is also commonly used in the synthesis of chiral compounds and prodrugs.

Method:
The method for preparing BOC-5-chloro-D-tryptophan is usually to react n-butyl butyrate with acetamidine to form acetamidine butyrate. The acetamidine ester is then subjected to a Sn2 substitution reaction with 5-chloro-D-tryptophan to produce BOC-5-chloro-D-tryptophan. Finally, the target product is purified by crystallization or column chromatography.

Safety Information:
BOC-5-chloro-D-tryptophan is a chemical that requires careful handling. Wear appropriate protective equipment such as gloves, goggles, and lab coats when operating. Avoid contact with skin and eyes to prevent irritation and injury. In addition, laboratory safety practices should be followed, and waste from the compound should be stored and disposed of properly.
Last Update:2024-04-09 21:00:56
114903-31-0
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SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: BOC-5-CHLORO-D-TRYPTOPHAN Visit Supplier Webpage Request for quotation
CAS: 114903-31-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
View History
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