108534-47-0
4-(Tert-Butyldimethylsilyloxy)Phenol
CAS: 108534-47-0
Molecular Formula: C12H20O2Si
108534-47-0 - Names and Identifiers
| Name | 4-(Tert-Butyldimethylsilyloxy)Phenol |
| Synonyms | 4-(t-Butyldimethylsilyloxy)Phenol 4-(Tert-Butyldimethylsilyloxy)Phenol 4-[tert-butyl(dimethyl)silyl]oxyphenol 4-([tert-Butyl(dimethyl)silyl]oxy)phenol 4-{[tert-butyl(dimethyl)silyl]oxy}phenol 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenol Phenol, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- |
| CAS | 108534-47-0 |
| InChI | InChI=1/C12H20O2Si/c1-12(2,3)15(4,5)14-11-8-6-10(13)7-9-11/h6-9,13H,1-5H3 |
108534-47-0 - Physico-chemical Properties
| Molecular Formula | C12H20O2Si |
| Molar Mass | 224.37 |
| Density | 0.974±0.06 g/cm3(Predicted) |
| Melting Point | 60-64 °C (lit.) |
| Boling Point | 266.4±23.0 °C(Predicted) |
| Flash Point | 114.9°C |
| Vapor Presure | 0.00526mmHg at 25°C |
| Appearance | Powder |
| Color | White to off-white |
| pKa | 10.24±0.15(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | 7: reacts slowly with moisture/water |
| Refractive Index | 1.49 |
| Physical and Chemical Properties | WGK Germany:3 |
108534-47-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| TSCA | No |
108534-47-0 - Introduction
4-(tert-butyl dimethyl siloxy) phenol is also known as tert-butyl dimethyl siloxy phenol (TBDMS-Phenol), its nature, use, preparation and safety information are as follows:
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C14H22O2Si
-Molecular weight: 250.42g/mol
-Solubility: Soluble in organic solvents such as chloroform, dimethylformamide and ether
Use:
-compound protecting group: TBDMS-Phenol can be used as a compound protecting group in chemical synthesis, which can protect hydroxyl groups in alcohol compounds to avoid unnecessary reactions and facilitate other chemical reactions.
-Organic synthesis: TBDMS-Phenol is widely used in organic synthesis and can be used to synthesize biologically active compounds.
-Chemical analysis: TBDMS-Phenol can be used for reagents and standards in organic chemical analysis.
Preparation Method:
-The preparation method of TBDMS-Phenol is generally obtained by reacting tert-butyl dimethyl chlorosilane with phenol. The specific steps include first subjecting tert-butyldimethylsilyl chloride and phenol to a condensation reaction under alkaline conditions to generate a TBDMS-Phenol product, which is then separated and purified to obtain the desired product.
Safety Information:
-The TBDMS-Phenol will not cause significant harm to the human body under normal operating conditions.
-As a chemical, follow laboratory safety procedures and personal protective measures.
- TBDMS-Phenol is a flammable liquid and should be kept away from open flames and high temperatures.
-Avoid contact with skin, eyes and respiratory tract during use. In case of contact, rinse immediately with plenty of water and seek medical help.
-Store sealed, away from fire and oxidizing agents.
Nature:
-Appearance: Colorless to light yellow liquid
-Molecular formula: C14H22O2Si
-Molecular weight: 250.42g/mol
-Solubility: Soluble in organic solvents such as chloroform, dimethylformamide and ether
Use:
-compound protecting group: TBDMS-Phenol can be used as a compound protecting group in chemical synthesis, which can protect hydroxyl groups in alcohol compounds to avoid unnecessary reactions and facilitate other chemical reactions.
-Organic synthesis: TBDMS-Phenol is widely used in organic synthesis and can be used to synthesize biologically active compounds.
-Chemical analysis: TBDMS-Phenol can be used for reagents and standards in organic chemical analysis.
Preparation Method:
-The preparation method of TBDMS-Phenol is generally obtained by reacting tert-butyl dimethyl chlorosilane with phenol. The specific steps include first subjecting tert-butyldimethylsilyl chloride and phenol to a condensation reaction under alkaline conditions to generate a TBDMS-Phenol product, which is then separated and purified to obtain the desired product.
Safety Information:
-The TBDMS-Phenol will not cause significant harm to the human body under normal operating conditions.
-As a chemical, follow laboratory safety procedures and personal protective measures.
- TBDMS-Phenol is a flammable liquid and should be kept away from open flames and high temperatures.
-Avoid contact with skin, eyes and respiratory tract during use. In case of contact, rinse immediately with plenty of water and seek medical help.
-Store sealed, away from fire and oxidizing agents.
Last Update：2024-04-10 22:29:15
Supplier List
Spot supply
Product Name: 4-((tert-Butyldimethylsilyl)oxy)phenol Request for quotationCAS: 108534-47-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-(tert-Butyldimethylsiloxy)phenol Visit Supplier Webpage Request for quotationCAS: 108534-47-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENOL9& Visit Supplier Webpage Request for quotationCAS: 108534-47-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENOL 9& Visit Supplier Webpage Request for quotationCAS: 108534-47-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 4-[tert-butyl(dimethyl)silyl]oxyphenol Visit Supplier Webpage Request for quotation
CAS: 108534-47-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 108534-47-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 4-((tert-Butyldimethylsilyl)oxy)phenol Request for quotationCAS: 108534-47-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-(tert-Butyldimethylsiloxy)phenol Visit Supplier Webpage Request for quotationCAS: 108534-47-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENOL9& Visit Supplier Webpage Request for quotationCAS: 108534-47-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENOL 9& Visit Supplier Webpage Request for quotationCAS: 108534-47-0
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 4-[tert-butyl(dimethyl)silyl]oxyphenol Visit Supplier Webpage Request for quotation
CAS: 108534-47-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 108534-47-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History