1077-97-0
5-iodo-1H-indazole-3-carboxylic acid
CAS: 1077-97-0;677702-22-6
Molecular Formula: C8H5IN2O2
1077-97-0 - Names and Identifiers
| Name | 5-iodo-1H-indazole-3-carboxylic acid |
| Synonyms | 5-Iodoindazole-3-carboxylic acid 5-iodo-1H-indazole-3-carbaldehyde 5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID 5-iodo-1H-indazole-3-carboxylic acid 5-IODO-3-(1H)INDAZOLE CARBOXYLIC ACID 1H-Indazole-3-carboxylic acid, 5-iodo- 1H-indazole-3-carboxylic acid, 5-iodo- |
| CAS | 1077-97-0 677702-22-6 |
| InChI | InChI=1/C8H5IN2O/c9-5-1-2-7-6(3-5)8(4-12)11-10-7/h1-4H,(H,10,11) |
1077-97-0 - Physico-chemical Properties
| Molecular Formula | C8H5IN2O2 |
| Molar Mass | 288.04 |
| Density | 2.220±0.06 g/cm3(Predicted) |
| Melting Point | 375℃ |
| Boling Point | 512.1±30.0 °C(Predicted) |
| Flash Point | 217.2°C |
| Vapor Presure | 8.66E-08mmHg at 25°C |
| pKa | 2.84±0.30(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.824 |
1077-97-0 - Introduction
5-iodine -1H-indole oxazole -3-carboxylic acid is an organic compound, its chemical structure contains indole ring and formic acid group, at the same time there is an iodine atom substituted in the indole ring on the fifth carbon atom.
Regarding its properties, 5-iodo-1H-indolazole-3-carboxylic acid is a solid with the appearance of white crystals. Its melting point at room temperature and pressure is 192-196 degrees Celsius. This compound has a certain solubility and is soluble in common organic solvents such as methanol, ethanol and dimethylformamide.
5-iodo-1H-indolazole-3-carboxylic acid has certain application value in pharmaceutical chemistry, which is mainly used for the synthesis of biologically active compounds containing indole groups. Indole groups have a wide range of applications in medicinal chemistry, for example as precursors for anti-tumor, anti-inflammatory and anti-viral drugs.
The compound can be prepared by reacting indole with methyl iodide. First, indole is dissolved in an appropriate solvent, and methyl iodide is added as a substitution reagent, and the reaction is carried out under appropriate conditions. After completion of the reaction, the target product can be obtained through separation and purification.
Regarding safety information, 5-iodo-1H-indolazole-3-carboxylic acid requires personal protective measures when handling. Wear appropriate protective gloves, glasses and laboratory clothing during operation to avoid contact with skin or inhalation of gases. In addition, chemicals need to be stored in a dark, dry and well-ventilated place, away from fire and oxidizing agents. When using the compound, correct operating procedures should be followed and the laboratory's safe operating instructions should be strictly followed.
Regarding its properties, 5-iodo-1H-indolazole-3-carboxylic acid is a solid with the appearance of white crystals. Its melting point at room temperature and pressure is 192-196 degrees Celsius. This compound has a certain solubility and is soluble in common organic solvents such as methanol, ethanol and dimethylformamide.
5-iodo-1H-indolazole-3-carboxylic acid has certain application value in pharmaceutical chemistry, which is mainly used for the synthesis of biologically active compounds containing indole groups. Indole groups have a wide range of applications in medicinal chemistry, for example as precursors for anti-tumor, anti-inflammatory and anti-viral drugs.
The compound can be prepared by reacting indole with methyl iodide. First, indole is dissolved in an appropriate solvent, and methyl iodide is added as a substitution reagent, and the reaction is carried out under appropriate conditions. After completion of the reaction, the target product can be obtained through separation and purification.
Regarding safety information, 5-iodo-1H-indolazole-3-carboxylic acid requires personal protective measures when handling. Wear appropriate protective gloves, glasses and laboratory clothing during operation to avoid contact with skin or inhalation of gases. In addition, chemicals need to be stored in a dark, dry and well-ventilated place, away from fire and oxidizing agents. When using the compound, correct operating procedures should be followed and the laboratory's safe operating instructions should be strictly followed.
Last Update：2024-04-09 21:54:55
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Multiple SpecificationsSpot supply
Product Name: 5-Iodo-1H-indazole-3-carbaldehyde Request for quotationCAS: 677702-22-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Multiple Specifications
Product Name: 5-IODO-1H-INDAZOLE-3-CARBOXYLIC ACID Visit Supplier Webpage Request for quotationCAS: 1077-97-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
1077-97-0
848819-86-3
905307-04-2
10027-07-3
73962-07-9
542-14-3
67506-86-9
Ntylon-12
1260784-30-2
51632-40-7
848819-86-3
905307-04-2
10027-07-3
73962-07-9
542-14-3
67506-86-9
Ntylon-12
1260784-30-2
51632-40-7