1076197-05-1
4-(4-Bromophenyl)-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-4-piperidinecarboxylic acid
CAS: 1076197-05-1
Molecular Formula: C17H22BrNO4
1076197-05-1 - Names and Identifiers
1076197-05-1 - Physico-chemical Properties
| Molecular Formula | C17H22BrNO4 |
| Molar Mass | 384.26 |
| Density | 1.393±0.06 g/cm3(Predicted) |
| Boling Point | 484.4±45.0 °C(Predicted) |
| pKa | 3.96±0.20(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD11226814 |
1076197-05-1 - Introduction
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid is an organic compound with the following properties:
1. Appearance: White crystalline solid.
2. molecular formula: C16H18BrNO4.
3. Molecular weight: 370.22g/mol.
4. Solubility: Soluble in organic solvents such as methanol, ethanol and dimethylformamide, almost insoluble in water.
Its main uses are:
1. As a protecting group in organic synthesis: Boc protecting group can protect the amine group to prevent unnecessary side reactions in the reaction.
2. For the preparation of pharmaceutical intermediates: The compound can be used to synthesize various drugs, such as anti-tumor drugs.
Preparation Method:
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid can be synthesized by the following steps:
1. First, 4-bromobenzyl alcohol and ethyl N,N-dimethylcarbamate were reacted to obtain 4-(4-bromophenyl)-4-piperidinemethanol.
2. Next, 4-(4-bromophenyl)-4-piperidinemethanol and ethyl N-butyldimethylcarbamate were reacted to obtain 1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid.
Safety Information:
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid is an organic compound and requires the following safety precautions:
1. Avoid contact with skin and eyes to avoid irritation and damage.
2. During operation, ensure good ventilation conditions.
3. avoid inhalation of its dust or steam.
4. use to wear appropriate personal protective equipment, such as gloves and protective glasses.
5. Waste must be disposed of in accordance with local regulations.
1. Appearance: White crystalline solid.
2. molecular formula: C16H18BrNO4.
3. Molecular weight: 370.22g/mol.
4. Solubility: Soluble in organic solvents such as methanol, ethanol and dimethylformamide, almost insoluble in water.
Its main uses are:
1. As a protecting group in organic synthesis: Boc protecting group can protect the amine group to prevent unnecessary side reactions in the reaction.
2. For the preparation of pharmaceutical intermediates: The compound can be used to synthesize various drugs, such as anti-tumor drugs.
Preparation Method:
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid can be synthesized by the following steps:
1. First, 4-bromobenzyl alcohol and ethyl N,N-dimethylcarbamate were reacted to obtain 4-(4-bromophenyl)-4-piperidinemethanol.
2. Next, 4-(4-bromophenyl)-4-piperidinemethanol and ethyl N-butyldimethylcarbamate were reacted to obtain 1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid.
Safety Information:
1-Boc-4-(4-bromophenyl)-4-piperidinecarboxylic acid is an organic compound and requires the following safety precautions:
1. Avoid contact with skin and eyes to avoid irritation and damage.
2. During operation, ensure good ventilation conditions.
3. avoid inhalation of its dust or steam.
4. use to wear appropriate personal protective equipment, such as gloves and protective glasses.
5. Waste must be disposed of in accordance with local regulations.
Last Update：2024-04-09 21:21:28
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Product Name: 1-BOC-4-(4-BROMOPHENYL)-4-PIPERIDINECARBOXYLIC ACID Request for quotationCAS: 1076197-05-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 4-(4-Bromophenyl)-1-tert-butoxycarbonyl-piperidine-4-carboxylic acid Visit Supplier Webpage Request for quotationCAS: 1076197-05-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 1-BOC-4-(4-BROMOPHENYL)-4-PIPERIDINECARBOXYLIC ACID Visit Supplier Webpage Request for quotationCAS: 1076197-05-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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