1029636-03-0
3-(4-Fluorophenyl)pyrrolidine hydrochloride
CAS: 1029636-03-0
Molecular Formula: C10H13ClFN
1029636-03-0 - Names and Identifiers
| Name | 3-(4-Fluorophenyl)pyrrolidine hydrochloride |
| Synonyms | 3-(4-Fluorophenyl)pyrrolidine hydrochloride Pyrrolidine, 3-(4-fluorophenyl)-, hydrochloride (1 |
| CAS | 1029636-03-0 |
1029636-03-0 - Physico-chemical Properties
| Molecular Formula | C10H13ClFN |
| Molar Mass | 201.6683232 |
| Storage Condition | 2-8°C |
1029636-03-0 - Introduction
3-(4-fluorophenyl) pyrrolidine hydrochloride is an organic compound. Its chemical formula is C11H9FN · HCl and it is a white solid. Here are some of its properties, uses, methods and safety information:
Nature:
-Appearance: White crystal or crystalline powder
-melting point: about 218-220 ℃
-Solubility: It is not easy to dissolve in water, but it can be dissolved in some organic solvents, such as alcohols, ethers and ketones.
-Stability: It is relatively stable at room temperature, but will undergo hydrolysis under alkaline conditions.
Use:
-Pharmaceutical field: 3-(4-fluorophenyl) pyrrolidine hydrochloride can be used as an antipsychotic drug with high efficiency and low toxicity.
-Scientific research: It is often used as an intermediate or reagent in organic synthesis research.
Preparation Method:
The preparation of 3-(4-fluorophenyl) pyrrolidine hydrochloride is usually accomplished by the following steps:
1. 4-fluorophenyl pyrrolidine ester was prepared by esterification of 4-fluorobenzoic acid and pyrrolidine.
2. 4-Fluorophenyl pyrrolidine ester is reacted with hydrogen chloride to obtain 3-(4-fluorophenyl) pyrrolidine hydrochloride.
Safety Information:
- 3-(4-Fluorophenyl) pyrrolidine hydrochloride has no obvious toxicity or carcinogenicity under normal use, but it is still recommended to follow safe operating procedures.
-It may cause irritation to the eyes, skin and respiratory tract, so take appropriate protective measures such as gloves, masks and protective glasses when exposed.
-During storage, it should be kept in a closed container to avoid contact with oxygen, light and moisture. At the same time, keep away from fire and flammable materials.
Nature:
-Appearance: White crystal or crystalline powder
-melting point: about 218-220 ℃
-Solubility: It is not easy to dissolve in water, but it can be dissolved in some organic solvents, such as alcohols, ethers and ketones.
-Stability: It is relatively stable at room temperature, but will undergo hydrolysis under alkaline conditions.
Use:
-Pharmaceutical field: 3-(4-fluorophenyl) pyrrolidine hydrochloride can be used as an antipsychotic drug with high efficiency and low toxicity.
-Scientific research: It is often used as an intermediate or reagent in organic synthesis research.
Preparation Method:
The preparation of 3-(4-fluorophenyl) pyrrolidine hydrochloride is usually accomplished by the following steps:
1. 4-fluorophenyl pyrrolidine ester was prepared by esterification of 4-fluorobenzoic acid and pyrrolidine.
2. 4-Fluorophenyl pyrrolidine ester is reacted with hydrogen chloride to obtain 3-(4-fluorophenyl) pyrrolidine hydrochloride.
Safety Information:
- 3-(4-Fluorophenyl) pyrrolidine hydrochloride has no obvious toxicity or carcinogenicity under normal use, but it is still recommended to follow safe operating procedures.
-It may cause irritation to the eyes, skin and respiratory tract, so take appropriate protective measures such as gloves, masks and protective glasses when exposed.
-During storage, it should be kept in a closed container to avoid contact with oxygen, light and moisture. At the same time, keep away from fire and flammable materials.
Last Update：2024-04-09 21:11:58
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View History
1029636-03-0
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