tert-Butyl 4-(-5) piperidine-1-carboxylate is an organic compound with a chemical formula of C16H26N4O2 and a molecular weight of 310.40g/mol.
Nature:
tert-Butyl 4-(piperidine-1-carboxylate) is a solid with a white to light yellow color. It is a rare organic nitrogen heterocyclic compound with high thermal and chemical stability. It is stable at room temperature and soluble in many organic solvents such as chloroform, dichloromethane and dimethylformamide.
Use:
tert-Butyl 4-(piperidine-1-carboxylate) is a multifunctional reagent with a wide range of applications in organic synthesis. It is commonly used in the synthesis of heterocyclic compounds, pharmaceutical intermediates and bioactive molecules. It can be used as a synthetic starting material or intermediate for antibiotics, hormones, anticancer drugs, etc. In addition, it can also be used in the synthesis of ligands, conductors and fluorescent dyes.
Preparation Method:
the preparation of tert-Butyl 4-() piperidine-1-carboxylate is usually carried out by organic chemical synthesis route, the specific steps include the reaction of piperidine and chlorocarbyl chloride to obtain 4-piperidinyl chlorocarbyl chloride, and then the reaction with 4-amino-1H-pyrazole to generate the desired product. Finally, a tert-butyl protecting group (Boc protecting group) was introduced by reaction with tert-butyl methyl carbonate.
Safety Information:
tert-Butyl 4-(the piperidine-1-carboxylate) has low toxicity under normal use conditions. However, as an organic compound, it may be potentially irritating and allergenic. Wear protective gloves and eye protection when using, and operate in a well-ventilated place. If skin contact or inhalation occurs, rinse immediately with water and seek medical help.