1-acetylprolinamide
1-acetylprolinamide
CAS: 30130-35-9
Molecular Formula: C7H12N2O2
1-acetylprolinamide - Names and Identifiers
| Name | 1-acetylprolinamide |
| Synonyms | 1-acetylprolinamide 1-Acetyl-2-pyrrolidinecarboxamide 1-acetylpyrrolidine-2-carboxaMide 2-Pyrrolidinecarboxamide, 1-acetyl- 2-Pyrrolidinecarboxamide,1-acetyl-(6CI,9CI) |
| CAS | 30130-35-9 |
| InChI | InChI=1/C7H12N2O2/c1-5(10)9-4-2-3-6(9)7(8)11/h6H,2-4H2,1H3,(H2,8,11) |
1-acetylprolinamide - Physico-chemical Properties
| Molecular Formula | C7H12N2O2 |
| Molar Mass | 156.18 |
| Density | 1.206g/cm3 |
| Boling Point | 411.9°C at 760 mmHg |
| Flash Point | 202.9°C |
| Vapor Presure | 5.38E-07mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.519 |
1-acetylprolinamide - Introduction
1-acetylprolinamide is an organic compound with the chemical formula C7H10N2O2.
Its properties mainly include:
-Appearance: Colorless to light yellow crystalline solid.
-Melting point: 132-133 ° C.
-Solubility: better solubility in water, alcohols and ethers.
The main uses of 1-acetylprolinamide are:
-Biochemical research: used as a catalyst, intermediate or reagent in chemical synthesis and biological reactions.
-Pharmacy: As an intermediate in the synthesis of drugs, it is used to synthesize compounds with biological activity.
The method of preparing 1-acetylprolinamide is usually carried out by the following steps:
1.2-pyrrolidine carboxylic acid is reacted with anhydride to generate 2-pyrrolidine acid chloride.
2. React 2-pyrrolidine chloride with acetyl chloride to generate 1-acetyl -2-pyrrolidine chloride.
3. React 1-acetyl -2-pyrrolidine chloride with ammonia to generate 1-acetylprolinamide.
Regarding safety information, 1-acetylprolinamide has not been extensively studied for toxicity and harmfulness. During use or handling, laboratory safety practices should be observed, such as wearing appropriate personal protective equipment (such as gloves, glasses and laboratory coats), and avoiding inhalation, ingestion or contact with skin. It is recommended to use the compound under the guidance of a professional.
Its properties mainly include:
-Appearance: Colorless to light yellow crystalline solid.
-Melting point: 132-133 ° C.
-Solubility: better solubility in water, alcohols and ethers.
The main uses of 1-acetylprolinamide are:
-Biochemical research: used as a catalyst, intermediate or reagent in chemical synthesis and biological reactions.
-Pharmacy: As an intermediate in the synthesis of drugs, it is used to synthesize compounds with biological activity.
The method of preparing 1-acetylprolinamide is usually carried out by the following steps:
1.2-pyrrolidine carboxylic acid is reacted with anhydride to generate 2-pyrrolidine acid chloride.
2. React 2-pyrrolidine chloride with acetyl chloride to generate 1-acetyl -2-pyrrolidine chloride.
3. React 1-acetyl -2-pyrrolidine chloride with ammonia to generate 1-acetylprolinamide.
Regarding safety information, 1-acetylprolinamide has not been extensively studied for toxicity and harmfulness. During use or handling, laboratory safety practices should be observed, such as wearing appropriate personal protective equipment (such as gloves, glasses and laboratory coats), and avoiding inhalation, ingestion or contact with skin. It is recommended to use the compound under the guidance of a professional.
Last Update：2024-04-09 20:02:46
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View History
1-acetylprolinamide
Ferrous chloride tetrahydrate
6150-58-9
Acrylamido tertiary butyl sulfonic acid
329-15-7
柔软剂 I
ethyl-hexadecyl-dimethylazanium
Betahistine dihydrochloride
1-Dodecyl aldehyde
Antioxidant 626
Ferrous chloride tetrahydrate
6150-58-9
Acrylamido tertiary butyl sulfonic acid
329-15-7
柔软剂 I
ethyl-hexadecyl-dimethylazanium
Betahistine dihydrochloride
1-Dodecyl aldehyde
Antioxidant 626