1-Diphenylmethyl-3-azetid...
1-Benzhydrylazetidin-3-one
CAS: 40320-60-3
Molecular Formula: C16H15NO
1-Diphenylmethyl-3-azetid... - Names and Identifiers
| Name | 1-Benzhydrylazetidin-3-one |
| Synonyms | 1-benzhdrylazetidin-3-one 1-Benzhydrylazetidin-3-one 3-BENZHYDRYL-CYCLOBUTANONE 1-BENZHYDRYLAZETIDIN-3-ONE 1-Diphenylmethyl-3-azetid... 1-Diphenylmethyl-3-azetidinone 1-(Diphenylmethyl)azetidin-3-on 1-(Diphenylmethyl)azetidin-3-one 1-(DIPHENYLMETHYL)AZETIDIN-3-ONE 3-Azetidinone, 1-(diphenylmethyl)- |
| CAS | 40320-60-3 |
| InChI | InChI=1/C16H15NO/c18-15-11-17(12-15)16(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,16H,11-12H2 |
1-Diphenylmethyl-3-azetid... - Physico-chemical Properties
| Molecular Formula | C16H15NO |
| Molar Mass | 237.3 |
| Density | 1.182 |
| Melting Point | 75.0 to 79.0 °C |
| Boling Point | 350-355℃ |
| Flash Point | 156°(313°F) |
| Vapor Presure | 3.99E-05mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Orange to Green |
| pKa | 3.10±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.626 |
| MDL | MFCD00964539 |
| Physical and Chemical Properties | 1-diphenylmethylazetidin-3-one is yellow solid at room temperature and atmospheric pressure, the ketone carbonyl group on the Quaternary ring can be subjected to Wittig reaction to produce olefin products, and can also be subjected to corresponding condensation reaction with hydroxylamine. |
1-Diphenylmethyl-3-azetid... - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
1-Diphenylmethyl-3-azetid... - Reference Information
| Application | 1-diphenylmethylazetin-3-one is a ketone derivative and can be used as a pharmaceutical intermediate. |
| synthesis method | in argon environment, oxalyl chloride (8.61 ml, 100 mmol) is added to dimethyl sulfoxide (12.45 ml, 176 mmol) in dichloromethane (150 ml) solution at -78 ℃ for 30 minutes, and the obtained mixture is stirred and reacted at -78 ℃ for 30 minutes, drop addition of 1-benzoylazetin-3-ol (20g, 84 mmol) solution of dichloromethane (75 ml), the reaction mixture is stirred at -78°C for another hour, and then slowly add triethylamine (58.2 ml, 418 mmol). Let the reaction mixture slowly raise the temperature to 0°C, then quench the reaction with a saturated ammonium chloride aqueous solution (150 ml), and then extract with dichloromethane (3 times), the combined organic layer is washed with water and salt water, and anhydrous sodium sulfate is used. Dry and concentrate to obtain a yellow solid crude 1-benzylazetin-3-one (20.8g, 105%). Figure 2-Hydroxy-5-nitro-3-trifluoromethylpyridine synthesis route |
Last Update：2024-04-09 15:16:50
Supplier List
Spot supply
Product Name: 1-Benzhydrylazetidin-3-one Request for quotationCAS: 40320-60-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 1-benzhydrylazetidin-3-one Visit Supplier Webpage Request for quotationCAS: 40320-60-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 1-Benzhydrylazetidin-3-one Visit Supplier Webpage Request for quotationCAS: 40320-60-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 1-Benzhydryl-3-azetidinone Visit Supplier Webpage Request for quotationCAS: 40320-60-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 1-Benzhydrylazetidin-3-One Visit Supplier Webpage Request for quotation
CAS: 40320-60-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 40320-60-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Spot supply
Product Name: 1-Benzhydrylazetidin-3-one Request for quotationCAS: 40320-60-3
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 1-benzhydrylazetidin-3-one Visit Supplier Webpage Request for quotationCAS: 40320-60-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 1-Benzhydrylazetidin-3-one Visit Supplier Webpage Request for quotationCAS: 40320-60-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 1-Benzhydryl-3-azetidinone Visit Supplier Webpage Request for quotationCAS: 40320-60-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Product Name: 1-Benzhydrylazetidin-3-One Visit Supplier Webpage Request for quotation
CAS: 40320-60-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 40320-60-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History