1-(Methylsulfonyl)piperidin-4-amine
4-Amino-1-methanesulfonylpiperidine
CAS: 402927-97-3
Molecular Formula: C6H14N2O2S
1-(Methylsulfonyl)piperidin-4-amine - Names and Identifiers
| Name | 4-Amino-1-methanesulfonylpiperidine |
| Synonyms | AKOS B025717 ART-CHEM-BB B025717 4-AMINO-1-METHANESULFONYLPIPERIDINE 4-Amino-1-methanesulfonylpiperidine 1-(METHYLSULFONYL)PIPERIDIN-4-AMINE 1-(Methylsulfonyl)piperidin-4-amine 1-Methanesulfonyl-piperidin-4-ylamine 4-Amino-N-1-(methylsulfonyl)piperidine 1-(methylsulfonyl)-4-piperidinamine 1HCl |
| CAS | 402927-97-3 |
| InChI | InChI=1/C6H14N2O2S/c1-11(9,10)8-4-2-6(7)3-5-8/h6H,2-5,7H2,1H3 |
1-(Methylsulfonyl)piperidin-4-amine - Physico-chemical Properties
| Molecular Formula | C6H14N2O2S |
| Molar Mass | 178.25 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Boling Point | 296.0±50.0 °C(Predicted) |
| Flash Point | 132.8°C |
| Vapor Presure | 0.00147mmHg at 25°C |
| pKa | 9.45±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.54 |
1-(Methylsulfonyl)piperidin-4-amine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
1-(Methylsulfonyl)piperidin-4-amine - Introduction
It is an organic compound with the chemical formula C6H14N2O2S. It is a white crystalline powder with a pungent ammonia flavor.
One of its main uses is as an intermediate in organic synthesis. It can be used to synthesize various drugs and pesticides, including antibiotics, anticancer drugs and various insecticides. It can also be used as a raw material for certain buffers and surfactants.
The preparation of the
phosphor is generally accomplished by introducing a methanesulfonyl group into the aminopiperidine. A commonly used preparation method is to add 1-methylsulfonylchloromethyl to an aminopiperidine solution to form the target product under the action of a base.
When using and handling, you need to pay attention to the following safety information. First, it is an irritant substance that can cause irritation in contact with the skin and eyes. Therefore, protective gloves, goggles and protective clothing should be worn during operation. Secondly, it can enter the human body through inhalation and ingestion, so it is necessary to ensure that it is operated in a well-ventilated place and avoid accidental ingestion. In addition, it can be decomposed at high temperatures to produce toxic gases, so stay away from fire and high temperature environments. Finally, it should be stored in a dry and ventilated place, isolated from oxidants and strong acids to avoid accidents.
One of its main uses is as an intermediate in organic synthesis. It can be used to synthesize various drugs and pesticides, including antibiotics, anticancer drugs and various insecticides. It can also be used as a raw material for certain buffers and surfactants.
The preparation of the
phosphor is generally accomplished by introducing a methanesulfonyl group into the aminopiperidine. A commonly used preparation method is to add 1-methylsulfonylchloromethyl to an aminopiperidine solution to form the target product under the action of a base.
When using and handling, you need to pay attention to the following safety information. First, it is an irritant substance that can cause irritation in contact with the skin and eyes. Therefore, protective gloves, goggles and protective clothing should be worn during operation. Secondly, it can enter the human body through inhalation and ingestion, so it is necessary to ensure that it is operated in a well-ventilated place and avoid accidental ingestion. In addition, it can be decomposed at high temperatures to produce toxic gases, so stay away from fire and high temperature environments. Finally, it should be stored in a dry and ventilated place, isolated from oxidants and strong acids to avoid accidents.
Last Update：2024-04-09 21:01:54
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View History
1-(Methylsulfonyl)piperidin-4-amine
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate
Acetic acid, cyclopentylphenyl-
methyl 4-(2-(trimethylsilyl)ethynyl)benzoate
Acetic acid, cyclopentylphenyl-