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1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine

cloperastine

CAS: 3703-76-2

Molecular Formula: C20H24ClNO

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1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine - Names and Identifiers

Name cloperastine
Synonyms HT 11
BRN 0275589
cloperastine
Cloperastine
CLOPERASTINE
Cloperastina
Cloperastinum
UNII-69M5L7BXEK
Cloperastine [INN]
Cloperastinum [INN-Latin]
Cloperastina [INN-Spanish]
5-20-02-00105 (Beilstein Handbook Reference)
1-[2-[p-Chloro-phenylbenzyl)-oxy]ethy]piperidine
1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine
1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)-piperidin
1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)piperidine
1-(2-[(4-Chlorophenyl)(phenyl)methoxy]ethyl)piperidine
1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine
1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)-piperidin
1- 2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl piperidine
1-{2-((p-Chloro-alpha-phenylbenzyl)oxy)ethyl}piperidine
1-{2-[(p-Chloro-alpha-phenylbenzyl)oxy]ethyl}piperidine
Piperidine, 1-(2-((p-chloro-alpha-phenylbenzyl)oxy)ethyl)-
Piperidine, 1-(2-((4-chlorophenyl)phenylmethoxy)ethyl)- (9CI)
CAS 3703-76-2
EINECS 223-042-3
InChI InChI=1/C20H24ClNO/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22/h1,3-4,7-12,20H,2,5-6,13-16H2

1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine - Physico-chemical Properties

Molecular FormulaC20H24ClNO
Molar Mass329.87
Density1.0383 (rough estimate)
Boling Pointbp0.06 172-174°; bp0.15 178-180°
Flash Point210.2°C
Vapor Presure2.15E-07mmHg at 25°C
pKa8.69±0.10(Predicted)
Storage ConditionRoom Temprature
Refractive Index1.5790 (estimate)
Physical and Chemical PropertiesBoiling point 178-180 °c (20Pa),172-174 °c (8PA), its hydrochloride, C20H24CINO. HCI,Hustazol. White or off-white crystalline powder. Melting point 147.9 °c. Soluble in water, ethanol, chloroform, acetone-soluble. There was no odor, and there was numbness after the taste of octyl.
UseFor the treatment of acute upper respiratory tract inflammation, chronic bronchitis and tuberculosis caused by frequent Cough

1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine - Risk and Safety

ToxicityLD50 unreported in guinea pig: 439mg/kg

1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine - Reference

Reference
Show more
1. [IF=3.591] Meng Li et al."Chiral separation of five antihistamine drug enantiomers and enantioselective pharmacokinetic study of carbinoxamine in rat plasma by HPLC-MS/MS."New J Chem. 2020 Apr;44(15):5819-5827
1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine
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Shanghai Yuanye Bio-Technology Co., Ltd.
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CAS: 3703-76-2
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Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: CLOPERASTINE Visit Supplier Webpage Request for quotation
CAS: 3703-76-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Zouping Mingxing Chemical Co., Ltd.
Product Name: Cloperastine Request for quotation
CAS: 3703-76-2
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
WhatsApp: 13605431940
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1-(2-((4-Chlorophenyl)phenylmethoxy)ethyl)piperidine
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