-Diformyl

-Diformyl - Names and Identifiers

Name	Posaconazole Impurity 43
Synonyms	-Diformyl Posaconazole Impurity 43 Desethylene Posaconazole N,N'-Diformyl Posaconazole Desethylene Diformyl Impurity Desethylene Posaconazole N(triazolonophenyl)-Formyl N-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-N-(2-(N-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)formamido)ethyl)formamide N-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-N-(2-(N-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)formamido)ethyl)formamide
CAS	357189-95-8

-Diformyl - Physico-chemical Properties

Molecular Formula	C37H40F2N8O6
Molar Mass	730.7603064
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	Light Brown to Brown
Storage Condition	Hygroscopic, -20°C Freezer, Under inert atmosphere

-Diformyl - Introduction

Posaconazole imidazolidine is an impurity that is a by-product of posaconazole, also known as one of the major degradation products of posaconazole.

The properties of posaconazole imidazolidine are as follows:
-Appearance: Common as a colorless solid
-Solubility: Soluble in organic solvents such as ethanol, acetone and dichloromethane, insoluble in water
-Stability: relatively unstable under light, heat, humidity and acidic conditions, easy to degrade

The main use of posaconazole imidazolidine is to conduct research and analysis as a degradation product of the antifungal drug posaconazole to understand the stability and degradation pathway of posaconazole.

In terms of preparation, posaconazole imidazolidine is usually produced in posaconazole by light or other conditions. The specific preparation method requires laboratory conditions for operation.

In terms of safety information, because posaconazole imidazolidine is a by-product, its toxicity and safety studies are relatively few. When using and handling, it is recommended to take standard laboratory safety practices to avoid direct contact with the skin and inhalation of its dust. In case of contact or misuse, medical advice should be sought immediately.

Last Update：2024-04-09 21:50:46