(S)-tetrahydro-2H-pyran-3-amine hydrochloride (often abbreviated as (S)-THP-HCl) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C7H15NO · HCl
-Molecular weight: 167.66g/mol
-melting point: 170-174 ℃
-Solubility: Soluble in water, ethanol and chloroform.
Use:
(S)-THP-HCl has a wide range of applications in organic synthesis and is often used as a protecting group. It can generate stable compounds by reacting with nucleophiles to prevent non-selective reactions of other moieties. In the synthesis of complex organic molecules, the use of (S)-THP-HCl can ensure the selective reaction of certain groups and their removal when necessary.
Preparation Method:
The preparation of (S)-THP-HCl is usually carried out by the following steps:
1. Reaction of (S)-3-amino -1, 2-propanediol with hydrochloric acid to produce (S)-THP-HCl.
Safety Information:
- (S)-THP-HCl is an organic compound, and attention should be paid to safe operation when using it.
-Avoid inhaling dust, contact with skin and eyes. If you come into contact with it, rinse immediately with water.
-Avoid dust during operation and operate in a well-ventilated place.
-When storing, keep it in a dry, cool place and avoid contact with oxidants.
Please note that the use and operation of chemicals should follow the correct laboratory safety operating procedures and follow relevant laws and regulations.