(R)-1-(4-Chloro-3-fluorophenyl)ethanamine
(R)-1-(4-Chloro-3-fluorophenyl)ethanamine
CAS: 1114559-14-6
Molecular Formula: C8H9ClFN
(R)-1-(4-Chloro-3-fluorophenyl)ethanamine - Names and Identifiers
(R)-1-(4-Chloro-3-fluorophenyl)ethanamine - Physico-chemical Properties
| Molecular Formula | C8H9ClFN |
| Molar Mass | 173.62 |
| Density | 1.215 |
| Boling Point | 226.7±25.0 °C(Predicted) |
| pKa | 8.50±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
(R)-1-(4-Chloro-3-fluorophenyl)ethanamine - Introduction
(R)-1-(4-chloro-3-fluorophenyl) ethanamine (also known as (R)-3-chloro-4-fluorophenethylamine) is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Molecular formula: C8H8ClFN
-Molecular weight: 175.61g/mol
-Appearance: colorless or yellowish liquid
-Melting point:-17 ℃
-Boiling point: 172-173 ℃
-Density: 1.269g/cm³(20 ℃)
-Refractive index: 1.531 (20 ℃)
-Optical rotation:[α]D25 = 117.7 ° (c = 1, methanol)
Use:
(R)-1-(4-chloro-3-fluorophenyl) ethylamine is a chiral pharmaceutical intermediate that can be used to synthesize biologically active compounds. It is often used as a chemical reagent in organic synthesis, medicine, pesticide and other fields.
Preparation Method:
The preparation method of (R)-1-(4-chloro-3-fluorophenyl) ethylamine can be carried out by the following steps:
1. the chloro-trifluorobenzene and ethylamine are placed in an organic solvent to react.
2. Using a suitable chiral carrier, a gold-gilling hydrogenation reaction is carried out through a reaction of a chiral ligand catalyst to obtain the target compound.
Safety Information:
(R)-1-(4-chloro-3-fluorophenyl) ethylamine is generally safe under correct use and storage, but some safety precautions still need to be paid attention:
-This compound is irritating, avoid contact with skin, eyes and mucous membranes.
-Follow appropriate laboratory safety procedures, such as wearing protective glasses, gloves and protective clothing.
-Avoid directly inhaling its vapor or dust, and operate in a well-ventilated place.
-When storing, keep it in a dry, cool place to avoid contact with oxidants or high temperature areas.
-In case of discomfort or misuse, seek medical attention immediately and bring information about the compound.
Nature:
-Molecular formula: C8H8ClFN
-Molecular weight: 175.61g/mol
-Appearance: colorless or yellowish liquid
-Melting point:-17 ℃
-Boiling point: 172-173 ℃
-Density: 1.269g/cm³(20 ℃)
-Refractive index: 1.531 (20 ℃)
-Optical rotation:[α]D25 = 117.7 ° (c = 1, methanol)
Use:
(R)-1-(4-chloro-3-fluorophenyl) ethylamine is a chiral pharmaceutical intermediate that can be used to synthesize biologically active compounds. It is often used as a chemical reagent in organic synthesis, medicine, pesticide and other fields.
Preparation Method:
The preparation method of (R)-1-(4-chloro-3-fluorophenyl) ethylamine can be carried out by the following steps:
1. the chloro-trifluorobenzene and ethylamine are placed in an organic solvent to react.
2. Using a suitable chiral carrier, a gold-gilling hydrogenation reaction is carried out through a reaction of a chiral ligand catalyst to obtain the target compound.
Safety Information:
(R)-1-(4-chloro-3-fluorophenyl) ethylamine is generally safe under correct use and storage, but some safety precautions still need to be paid attention:
-This compound is irritating, avoid contact with skin, eyes and mucous membranes.
-Follow appropriate laboratory safety procedures, such as wearing protective glasses, gloves and protective clothing.
-Avoid directly inhaling its vapor or dust, and operate in a well-ventilated place.
-When storing, keep it in a dry, cool place to avoid contact with oxidants or high temperature areas.
-In case of discomfort or misuse, seek medical attention immediately and bring information about the compound.
Last Update：2024-04-09 19:05:44
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Product Name: (R)-1-(4-Chloro-3-fluorophenyl)ethanamine Request for quotationCAS: 1114559-14-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: (R)-1-(4-chloro-3-fluorophenyl)ethan-1-amine Visit Supplier Webpage Request for quotationCAS: 1114559-14-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Product Name: (R)-1-(4-Chloro-3-fluorophenyl)ethanamine Visit Supplier Webpage Request for quotation
CAS: 1114559-14-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1114559-14-6
Tel: 18301782025
Email: 3008007409@qq.com
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View History
(R)-1-(4-Chloro-3-fluorophenyl)ethanamine
3,4-BIS(METHOXYCARBONYL)PHENYLBORONIC ACID
1,2,3-Propanetriyl trioctadecanoate
(R)-N-BOC-3-PYRROLIDINEACETIC ACID
Boc-b-HoAla(4-pyridyl)-OH
4-Propyl-2-methoxyphenol (4-propylguaiacol)
17a-methyl-17b-hydroxy-1,4-androstadien-3-one
N-(2,4-DIFLUORO-PHENYL)-MALONAMIC ACID
2-methyl-1,3-benzoxazol-5-ol
Phenyl(3-pyrrolidinyl)methanone hydrochloride (1:1)
3,4-BIS(METHOXYCARBONYL)PHENYLBORONIC ACID
1,2,3-Propanetriyl trioctadecanoate
(R)-N-BOC-3-PYRROLIDINEACETIC ACID
Boc-b-HoAla(4-pyridyl)-OH
4-Propyl-2-methoxyphenol (4-propylguaiacol)
17a-methyl-17b-hydroxy-1,4-androstadien-3-one
N-(2,4-DIFLUORO-PHENYL)-MALONAMIC ACID
2-methyl-1,3-benzoxazol-5-ol
Phenyl(3-pyrrolidinyl)methanone hydrochloride (1:1)