(1R,3R)-N-BOC-1-氨基环戊烷-3-甲酸

(1R,3R)-N-BOC-1-氨基环戊烷-3-甲酸 - Names and Identifiers

Name	Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(1R,3R)-
Synonyms	(1R,3R)-3-(Boc-amino)cyclopentanecarboxylic acid (1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID 3-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid (1R,3R)-N-tert-Butoxycarbonyl-1-aminocyclopentane-3-carboxylic acid Cyclopentanecarboxylic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(1R,3R)- (1r,3r)-3-[(2-methylpropan-2-yl)oxycarbonylamino]cyclopentane-1-carboxylic Acid
CAS	489446-85-7

(1R,3R)-N-BOC-1-氨基环戊烷-3-甲酸 - Physico-chemical Properties

Molecular Formula	C11H19NO4
Molar Mass	229.27
Density	1.15±0.1 g/cm3(Predicted)
Melting Point	117.3°C
Boling Point	382.5±31.0 °C(Predicted)
Appearance	Powder
Color	White to light yellow
pKa	4.62±0.40(Predicted)
Storage Condition	2-8°C

(1R,3R)-N-BOC-1-氨基环戊烷-3-甲酸 - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29221985

(1R,3R)-N-BOC-1-氨基环戊烷-3-甲酸 - Introduction

Cyclopentanecarboxylic acid, 3-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(1R,3R)-, the chemical formula is Cyclopentanecarboxylic acid, 3-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(1R,3R)-, is an organic compound.

Nature:
Cyclopentanecarboxylic acid, 3-[[(1,1-dimethyllethoxy) carbonyl]amino]-,(1R,3R)-is a white crystalline solid, soluble in organic solvents such as methanol and dimethyl sulfoxide. It is an asymmetric stereoisomer with a pair of chiral centers.

Use:
Cyclopentanecarboxylic acid, 3-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(1R,3R)-are commonly used as amino-protecting reagents in organic synthesis. Its amino protecting group is BOC(tert-butyloxycarbonyl), which can protect the amino function in chemical reactions. This protecting group can be removed by a platinum hydride catalyst when desired, releasing the free amino group.

Preparation Method:
The preparation of Cyclopentanecarboxylic acid, 3-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(1R,3R)-is generally carried out by a chemical synthesis method. Cyclopentane can be used as the starting material, through a series of reaction steps, including alkylation, amination and esterification, and finally reacted with BOC-Cl (tert-butoxycarbonyl ammonium chloride) to obtain the target product.

Safety Information:
Cyclopentanecarboxylic the safety of acid, 3-[[(1,1-dimenthylethoxy) carbonyl]amino]-,(1R,3R)-is relatively high, but some basic laboratory safety operations still need to be paid attention. It may be irritating to the skin and eyes, so contact with the skin and eyes should be avoided during the operation. Inhalation or ingestion of the compound should also be avoided. During storage and handling, it should be stored in a sealed container, away from fire and oxidizing agents. Before use, the safety data sheet (SDS) of the chemical should be read and followed.

Last Update：2024-04-10 22:29:15