(+-)-exo-1-methyl-4-(1-methylethyl)-2-((2-methylphenyl)methoxy)-7-oxabicyclo
Cinmethylin
CAS: 87818-31-3
Molecular Formula: C18H26O2
(+-)-exo-1-methyl-4-(1-methylethyl)-2-((2-methylphenyl)methoxy)-7-oxabicyclo - Names and Identifiers
(+-)-exo-1-methyl-4-(1-methylethyl)-2-((2-methylphenyl)methoxy)-7-oxabicyclo - Physico-chemical Properties
| Molecular Formula | C18H26O2 |
| Molar Mass | 274.4 |
| Density | d20 1015 kg/m3 |
| Melting Point | 25°C |
| Boling Point | 313°C |
| Flash Point | 147°C |
| Vapor Presure | 0.000939mmHg at 25°C |
| Appearance | neat |
| Storage Condition | 0-6°C |
| Refractive Index | 1.4800 (estimate) |
| Physical and Chemical Properties | Boiling point 313°C |
(+-)-exo-1-methyl-4-(1-methylethyl)-2-((2-methylphenyl)methoxy)-7-oxabicyclo - Risk and Safety
| Risk Codes | R20 - Harmful by inhalation R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S23 - Do not breathe vapour. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S22 - Do not breathe dust. |
| UN IDs | UN3082 9/PG 3 |
| WGK Germany | 3 |
| RTECS | RN8762000 |
| HS Code | 29321900 |
| Toxicity | LD50 orally in rats: 4.5 g/kg; LD50 dermally in rabbits: >2 g/kg (Lee) |
(+-)-exo-1-methyl-4-(1-methylethyl)-2-((2-methylphenyl)methoxy)-7-oxabicyclo - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| toxicity | Acute oral LD50 in rats was 3960mg/kg (4500mg/kg), rabbit acute percutaneous LD50>2000mg/kg. The rabbit eyes have mild irritation, have a stimulating effect on the skin. Rats were fed for 13 weeks with a non-effective dose of 300mg/kg, rats were fed for 2 years with a non-effective dose of 100mg/kg, and mice were fed with 30mg/kg. No carcinogenic or mutagenic effect was noted. Rainbow trout LC50 6.6mg/L (96H), Daphnia LC50 7.2mg/L (48h). Quail oral LD50>2150mg/kg, wild duck> 5620mg/kg. |
| Application | selective internal-absorption conductivity type pre-emergence soil treatment agent, belonging to cineole herbicide, it can be absorbed by the root system of sensitive plants, transmitted to the growing point of root and bud through xylem, and inhibited the growth of meristem and made it dead. After entering the rice, cotton and other crops, it is easy to be metabolized into hydroxyl compounds, and combine with the glycosides in the plant to form conjugated compounds and lose toxicity. The application period of this product is wide, the dosage is small, and the control effect of Humulus scandens is excellent. For example, the rice field should be controlled to remove Humulus scandens, duck tongue grass, and anagrass. In the stage of transplanting seedlings for 5-8 days and 1.5 leaves of Humulus scandens, 10% emulsifiable concentrate (2-100/m2), toxic soil and spray can be used. During application, the water layer was maintained at 3-5cm and water retention at 5-7 days. The amount of weed control in dry land should be increased, for example, 82% emulsifiable concentrate 7.5~12.5/100 is used in the field of flowering, and the soil is treated before the seedling. |
| production method | using 1-pinene as a starting material, the preparation method is as follows. Preparation of terpenoid -4-alcohol 1-pinene 0.735mol,35% sulfuric acid 0.714mol, Catalyst 0.2g mixed homogeneously, stirred at 20~30 ℃ for 20h, then heated to 45 ℃, heat preservation reaction 8H. The water layer is discarded, 50g of 25% NaOH and 50g of isopropanol are added to the oil layer, and 48g of 1,4-cineole is refluxed and fractionated, with a content of 70%. After mixing 0.25mol of 1, 4-cineole, 0.96mol of 1, 3-propanediamine and 2.3g of lithium wire, stir the reaction at 110 ° C. For 9H, then cool to 50 ° C. And add 6ml of water, after stirring at 80 ° C. For 30min, the reaction solution was distilled under reduced pressure to separate most of the amines and terpene hydrocarbon compounds, and the residue was washed with water to obtain 40g of terpenin-4-ol, with a content of 81%. (±)-2-hydroxy-1-methyl-4-isopropyl-7-oxabicyclo [2,2,1] Preparation of heptane in turn 30.8g terpenoid -4-alcohol, 0.8g bis (2, 4-glutaric acid) vanadium oxide, 300mL of dichloroethane and 22g of 90% tert-butanol peroxide (reported in the literature also using tert-butyric acid) were added to the reactor, exothermic, Reflux reaction for 2h, and 10ml of ethylene glycol dimethyl ether solution containing 0.8g of p-toluenesulfonic acid, refluxing for 1.5h, cooling, 0.8g of anhydrous sodium acetate was added under stirring, filtered, concentrated, and distilled under reduced pressure to obtain 28.4g of product. Synthesis of cycloheptyl ether under the protection of nitrogen, 13.2g of 50% sodium hydroxide (washed with hexane),150mL of dried dimethylformamide, heated to 60 °c, the mixture of 42.5g of the product from the previous step and 75ml of dimethylformamide was added dropwise for about 3 hours, the reaction temperature was controlled at 60~70 ℃, then the temperature was cooled to 20 ℃, and 36.6G of 2-methylbenzyl chloride was added dropwise, after dropping for about 1.5H, the reaction temperature was 20~25 ℃, and then the reaction was stirred at room temperature for 6H. After the reaction, the reaction mixture was poured into 1000mL water and acidified with concentrated hydrochloric acid, the mixture was extracted three times with 200ml of hexane, and the extracts were combined, dried, filtered, and dedissolved in 64g of cycloheptyl ether. |
| category | pesticide |
| toxicity grade | poisoning |
| Acute toxicity | oral-rat LD50: 4500 mg/kg |
| flammability hazard characteristics | 10% emulsifiable concentrate flammability |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; It is stored and transported separately from food raw materials |
| extinguishing agent | dry powder, foam, sand |
Last Update：2024-04-09 20:52:54
Supplier List
Spot supply
Product Name: Cinmethylin Visit Supplier Webpage Request for quotationCAS: 87818-31-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Cinmethylin Visit Supplier Webpage Request for quotation
CAS: 87818-31-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 87818-31-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Cinmethylin Visit Supplier Webpage Request for quotationCAS: 87818-31-3
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Cinmethylin Visit Supplier Webpage Request for quotation
CAS: 87818-31-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 87818-31-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History