(+)-氯前列烯醇
(+)-Cloprostenol
CAS: 54276-21-0
Molecular Formula: C22H29ClO6
(+)-氯前列烯醇 - Names and Identifiers
(+)-氯前列烯醇 - Physico-chemical Properties
| Molecular Formula | C22H29ClO6 |
| Molar Mass | 424.92 |
| Density | 1.321 |
| Boling Point | 628.0±55.0 °C(Predicted) |
| pKa | 4.76±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| In vitro study | D-Cloprostenol and PGF2 alpha are equipotent, about 150 times more potent than dl-cloprostenol (P < 0.05) and approximately 280 times more potent than PGE1 in inhibiting [ 3 H]PGF2 alpha binding to corpus luteum cell membranes. However, d-cloprostenol and PGF2 alpha are about 10 times more potent than dl-cloprostenol and approximately 95 times more potent than PGE1 in myometrial cell membranes. |
| In vivo study | D-cloprostenol (15 g per head) is the lowest dose that consistently achieves abortion; D-cloprostenol causes mild adverse effects including salivation, defecation and hyperventilation in bitches weighing less than 10 kg. Intra-vesicle administration of a single low dose of d-cloprostenol is a safe and successful technique to induce abortion in the bitch. |
(+)-氯前列烯醇 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.353 ml | 11.767 ml | 23.534 ml |
| 5 mM | 0.471 ml | 2.353 ml | 4.707 ml |
| 10 mM | 0.235 ml | 1.177 ml | 2.353 ml |
| 5 mM | 0.047 ml | 0.235 ml | 0.471 ml |
Last Update：2024-01-02 23:10:35
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View History
(+)-氯前列烯醇
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