LJI308
LJI308(LJI308)
CAS: 1627709-94-7
化学式: C21H18F2N2O2
| 中文名 | LJI308 |
| 英文名 | LJI308 |
| 别名 | 化合物LJI308 RSK抑制剂(LJI308) 2,6-二氟-4-(4-吗啉苯基)吡啶-3-基)苯酚 |
| 英文别名 | LJI308 CS-2181 LJI 308 LJI-308 2,6-Difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]phenol Phenol, 2,6-difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]- |
| CAS | 1627709-94-7 |
| EINECS | 604-604-1 |
| 化学式 | C21H18F2N2O2 |
| 分子量 | 368.38 |
| 溶解度 | DMSO: ≥ 32 mg/mL |
| 存储条件 | Inert atmosphere,Store in freezer, under -20°C |
| 体外研究 | LJI308 inhibits S6K1 with an IC 50 of 0.8 μM. LJI308 inhibits YB-1 phosphorylation in CRC cells at concentrations of 5 to 25 μM. In a dose kinetics experiment, LJI308, starting at 2.5 μM, inhibits YB-1 phosphorylation in the KRAS mutated TNBC cell line MDA-MB-231 by approximately 86%. LJI308 effectively blocks RSK and YB-1 phosphorylation after EGF stimulation and after irradiation in KRAS wild-type HBL-100 cells. LJI308 (1-10 μM; 96 hours) decreases cell viability by up to 90%. Cell Viability Assay Cell Line: HTRY-LT cell lines Concentration: 1-10 μM Incubation Time: 96 hours Result: Decreased cell viability by up to 90%. |
LJI308 - 配置溶液浓度参考
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.715 ml | 13.573 ml | 27.146 ml |
| 5 mM | 0.543 ml | 2.715 ml | 5.429 ml |
| 10 mM | 0.271 ml | 1.357 ml | 2.715 ml |
| 5 mM | 0.054 ml | 0.271 ml | 0.543 ml |
最后更新：2024-01-02 23:10:35
供应商列表
现货供应
产品名: 2,6-二氟-4-(4-吗啉苯基)吡啶-3-基)苯酚 询盘CAS: 1627709-94-7
产地: 上海
包装: 1mg；10mg；50mg；5mg；25mg；2mg；1mL*10mM(in DMSO)；100mg；1mL*10mM(inDMSO)；1mLx10mM(inDMSO)；200mg
规格: 98%；99.73%
价格: 电话、微信、QQ、邮件
库存: 现货
电话: 400-968-2212
手机: 18916960931
电子邮件: 3623107365@qq.com
QQ: 3623107365
微信: 18916960931
产品描述: 2,6-二氟-4-(4-吗啉苯基)吡啶-3-基)苯酚，98%；99.73%，Amole/阿摩尔
现货供应
产品名: 2,6-二氟-4-(4-吗啉苯基)吡啶-3-基)苯酚 询盘CAS: 1627709-94-7
产地: 上海
包装: 1mg；10mg；50mg；5mg；25mg；2mg；1mL*10mM(in DMSO)；100mg；1mL*10mM(inDMSO)；1mLx10mM(inDMSO)；200mg
规格: 98%；99.73%
价格: 电话、微信、QQ、邮件
库存: 现货
电话: 400-968-2212
手机: 18916960931
电子邮件: 3623107365@qq.com
QQ: 3623107365
微信: 18916960931
产品描述: 2,6-二氟-4-(4-吗啉苯基)吡啶-3-基)苯酚，98%；99.73%，Amole/阿摩尔
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