中文名 | L-叠氮亮氨酸盐酸盐 |
英文名 | L-Azidonorleucine (hydrochloride) |
别名 | L-叠氮亮氨酸盐酸盐 6-叠氮-L-去甲亮氨酸HCL 6-叠氮-L-去甲亮氨酸盐酸盐 6-叠氮-L-去甲亮氨酸HCL,6-AZIDO-L-NORLEUCINE HCL |
英文别名 | H-Lys(N3)-OH.HCl 6-Azido-L-norleucine HCl L-Azidonorleucine hydrochloride Nε-Azido-L-Lysine hydrochloride (2S)-2-amino-6-azidohexanoic acid L-Azidonorleucine (hydrochloride) (S)-2-Amino-6-azidohexanoic acid hydrochloride (2S)-2-amino-6-azidohexanoic acid hydrochloride 6-Azido-L-norleucine HCl,L-Azidonorleucine hydrochloride |
CAS | 1454334-76-9 |
化学式 | C6H13ClN4O2 |
分子量 | 208.64602 |
存储条件 | -20℃,密封 |
外观 | 固体 |
体外研究 | CHO cells transfected with pMaRSC and incubated with L-Azidonorleucine (Anl; 1.5 mM; 6 h) are fixed, permeabilized, and treated with alkyne-TAMRA. The TAMRA fluorescence exclusively in the mCherry-expressing cells is observed, consistent with cell-selective incorporation of Anl into cellular proteins. |
体内研究 | When L-Azidonorleucine (ANL) is administered via the drinking water, an average daily L-Azidonorleucine intake of 0.9 mg/day/g of body weight for 21 d when aiming to label and identify neuronal populations of the brain are recommended. Lower dosages or shorter labeling times might be used for the labeling of other cell types. When L-Azidonorleucine is administered by i.p. injection, the testing different L-Azidonorleucine doses in the range of 4-400 mM are recommended. A 400 mM dosage administered by i.p. (i.p. volume: 10 ml/kg) once per day for 1 week is recommended for labeling some neuronal populations (such as excitatory neurons of the hippocampus). Lower dosages (e.g., 4 mM) can potentially be used for labeling other cell types or when longer labeling periods are desired. |
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