EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
pharmacological action | timolol is a non-selective β-adrenergic receptor antagonist, which can reduce aqueous humor production without obvious endogenous sympathomimetic activity and local anesthesia effect, and has no direct inhibitory effect on myocardium. Drop eye with 0.5% product once every 12 hours, the effect of lowering intraocular pressure is fast, and the intraocular pressure begins to drop 20-30 minutes after dropping the eye, reaching its peak after 1-2 hours, and can last for more than 12 hours. |
indications | timolol can be used for primary open-angle glaucoma, some secondary glaucoma, ocular hypertension, some primary angle-closure glaucoma and other glaucoma with ineffective drugs and surgery, the addition of this product can further enhance the intraocular pressure reduction effect. |
Side effects | The most common eye burning sensation and tingling. It can cause decreased tear secretion, decreased corneal perception, superficial punctate keratopathy, allergic conjunctivitis, etc. After the eye drops are absorbed, bradycardia and arrhythmia may also occur; dizziness, aggravating symptoms of myasthenia gravis, paresthesia, lethargy, insomnia; bronchospasm, respiratory failure, dyspnea, nasal congestion, and cough; cover up diabetic patients Hypoglycemia symptoms after insulin or hypoglycemic drugs. |
use | for the treatment of open angle glaucoma, aphakic glaucoma, secondary glaucoma, ocular hypertension, and also for the treatment of acute myocardial infarction Patients with recurrence, etc. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |